Exam 2: Injectable Anesthetics Flashcards

1
Q

What are the 3 categories of Injectable anesthetics?

A
  1. Dissociative anestheticss
  2. Barbiturates
  3. Non Barbiturates
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2
Q

What are the 2 dissociative anesthetics

A
  1. Ketamine

2. Tiletamine

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3
Q

What are the 2 subcategories of Barbiturates?

A
  1. Thiobarbiturates

2. Oxybarbitrates

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4
Q

What is the drug classified as a thiobarbiturate?

A

Thiopental

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5
Q

What are the 2 drugs in the subcategory Oxybarbiturate

A
  1. Phenobarbital

2. Pentobarbital

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6
Q

What are the 3 Non-Barbiturates?

A
  1. Propofol
  2. Alfaxalone
  3. Etomidate
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7
Q

Drug-induced central depression resulting in unconsciousness

A

General Aneshtesia

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8
Q

Drug- induced dissociation of the thalamocortical and limbic systems resulting in a catatonic state

A

Dissociative anasthesia

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9
Q

Characterized by vountary motor excitment and state of analgesia

A

Analgesia

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10
Q

What are the 5 stages of Anesthesia

A
  1. Analgesia
  2. Excitment phase
  3. Surgical anesthesia
  4. Medullary paralysis
  5. Death
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11
Q

Characterized by involuntary excitation or delirium

A

Excitment phase

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12
Q

What is the MOA of ketamine and tiletamine

A

Non- competitive NMDA receptor antagonists

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13
Q

Dissociative Anesthetics inhibits _____

A

Glutamate

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14
Q

What part of the nociception pathway does Ketamine and Tiletamine act on?

A

Modulation

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15
Q

T/F Dissociative Anesthetics can cross the BBB

A

T

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16
Q

What are the two efects of Dissociative Anesthetics on the CNS?

A
  1. Depression of sensory preception

2. Activation of limbic system (emotional/behavioral/memory)

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17
Q

Dissociative Anesthetics Induce which stages of anesthesia?

A

Stages 1 and 2

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18
Q

T/F. Dissociative Anesthetics cause the animal to lose complete consciousness

A

F. partial

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19
Q

What are the main effects of Dissociative Anesthetics

A
  1. Catalepsy

2. Analgesia

20
Q

CVS effects of Ketamine and Tiletamine

A

Inc. CO and HR

21
Q

T/F. Ketamine is a controlled substance

22
Q

What scheduled drug is ketamine?

23
Q

T/F. Tiletamine is a controlled drug

24
Q

What is triple dip?

A

for large animals

Guaifenesin + Xylazine + Ketamine

25
What is FLK
Fentanyl + Lidocaine + Ketamine
26
What is MLK?
Morphine + Lidocaine + Ketamine
27
What is Kitty magic?
Ketamine + Dexamedetomidine + Buprenorphine
28
What parts of the nociception pathway do Barbituates act on?
Perception and Modulation
29
What is the MOA of Barbituates
GABA agonists
30
What is the main effets of Barbiturates
Sedation and hypnosis
31
T/F. Barbiturates cause poor anesthesia
T
32
T/F. Barbiturates have anticonvulsant effects
T
33
CVS effects of Barbiturates
Hypotension due to Cardiac depression
34
Resp. system effects of Barbiturates
Dose-Dependent resp. depression
35
Ultra-Short acting Thiobarbiturate GABA receptor agonist
Thiopental
36
used for euthanasia
Pentobarbital
37
Propofol effects on CNS
Dose Dependent CNS Depression
38
Propofol effects on CVS
Vasodilation and hypotension
39
Propofol effects on Resp system
Dose dependent resp. depression
40
What is the risk with givine propofol to cats?
Heinz-body anemia
41
Most common non barbiturate
Propofol
42
Non- barbiturate neurosteroid
Alfaxalone
43
What is the MOA of Alfaxalone
GABA agonist
44
#1 non barbiturate choice for unstable patient
Etomidate
45
T/F. you can uses Etomidate in animals with heart dz
T
46
Which of the following should be avoided in patients with thraumatic brain injury a. Diazepam b. Propofol c. Ketamine d. Lidocaine
c. Ketamine
47
``` Which of the following is not considered an IV anesthetic induction agent? a. Ketamine b. Propofol C. Alfaxalone d. Fentanyl ```
D. Fentanyl