Exam #3 Flashcards

(47 cards)

1
Q

Different cells involved with the skin

A

Keratinocytes
Melanocytes
Dendritic cells
Merkel cells

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2
Q

Keratinocytes

A

Executors of the re-epithelialization process, where keratinocytes migrate, proliferate, and differentiate to restore the epidermal barrier.

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3
Q

Melanocytes

A

Melanin production

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4
Q

Dendritic cells

A

Professional antigen presenting cells that inform the fight against invasive pathogens while enforcing tolerance to self and harmless environmental antigens.

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5
Q

Merkel cells

A

Essential for light touch sensation and found in the skin of vertebrates.

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6
Q

Strata

The order of epidermal layers

Superficial to deep

A

Stratum corneum
Stratum licidum
Stratum granulosum
Stratum spinosum
Stratum basale

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7
Q

What cells are found in each of the epidermal layers

A

Keratinocytes
Melanocytes
Dendritic cells
Tactile epithelial cells

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8
Q

Epidermis

A

Stratified squamous epithelium

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9
Q

Dermis

A

Loose areolar
Dense irregular connective tissue

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10
Q

Subcutaneous tissue

A

Deepest layer of your skin

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11
Q

Function of subcutaneous tissue

A

Stores fat
Anchors skin to underlying structures
Shock absorber
Layer of insulation

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12
Q

What are the cells that make up skin color

A

Melanin
Carotene
Hemoglobin

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13
Q

Albinism

A

Inherited inability to produce melanin
Melanocytes lack the enzyme tyrosinase
Melanin absent in hair skin and eyes
There are different types of albinism
Vision problems occur abnormal development of retina

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14
Q

Vitiligo

A

Partial or complete loss of melanocytes in areas of the skin
Patchy white spots
Thought to be an autoimmune disease

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15
Q

Basal cell carcinoma

A

Epidermal cells invade into dermis

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16
Q

Squamous cell carcinoma

A

Second most common starts in stratum spinosum may spread to any other layer

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17
Q

Melanoma

A

Most deadly starts from melanocytes
Can develop in lungs and brain
Can travel through blood vessels

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18
Q

Eccrine sweat glands

A

Function throughout life
Most numerous widely distributed
Secretion sweat 99% water
Nacl, Vitamin C, Antibodies, Waste, Lactic acid, and Dermcidin
Regulation of body temp and excretion

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19
Q

Apocrine sweat glands

A

Located mainly in armpits and groin
Become active at puberty
Secretion is viscous and odorless
Same composition as sweat plus organic substances proteins and fats
Activity during periods of pain stress and sexual excitement

20
Q

What produces earwax

A

Ceruminous glands

21
Q

Functions of the skin

A

Protection chemical physical and biological
Regulation of body temp
Cutaneous sensation
Metabolic functions
Blood reservoir
Excretion

22
Q

Describe the hair follicle

A

Hair
Shaft
Root
Bulb
Hair papilla
Hair matrix
Sebaceous gland sebum
Arrector pili muscle

23
Q

What are the different cells located in bone tissue

A

Osteoprogenitor cells
Osteoblast cells
Osteoclast cells

24
Q

Osteoprogenitor

A

Stem cells dividing cells
Found on bone surfaces in the periosteum and endosteum
Some differentiate into osteoblasts

25
Osteoblast cells
Bone forming cells Dividing cells on bone surfaces Secrete organic components of matrix Help mineralize the bone matrix calcification
26
Osteoclast cells
Bone destroying cells Break down bone Parathyroid hormone increases their activity
27
Compact Bone
Osteon Structural unit Run parallel to bones long axis Lamellae layers Central canal blood vessels nerve fibers Perforating canals volkmann's canals Canaliculi osteocytes in lacunae
28
Spongy bone
No osteons Network of trabeculae thin bony plates contain lamellae osteocytes in lacunae and canaliculi Align along lines of stress
29
What are the different parts of osteon
Lacunae: tiny spaces that contain the osteocytes, or bone cells Canaliculi: small tunnels that connect one lacunae to another lacunae Lamellae: sheets of mineralized collagen that extend over hundreds of bone tissue Haversian canals: a series of tubes around narrow channels formed by lamellae
30
What is the process of intramembranous ossification
Ossification centers develop in the fibrous connective tissue membrane Osteoid is secreted and calcifies Immature spongy bone and periosteum form Compact bone replaces immature spongy bone just deep to the periosteum red marrow develops
31
What is the process of endochondral ossification
Bone collar forms around the diaphysis of the hyline cartilage model Cartilage in the center of the diaphysis calcifies and then develops cavities The periosteal bud invades the internal cavities and spongy bone forms The diaphysis elongates and a medullary cavity forms secondary ossification centers appear in the epiphyses The epiphyses ossify when completed hyaline cartilage remains only in the epiphyseal plates and articular cartilages
32
Where are the ossification centers located for primary and secondary
Primary forms in the diaphyseal region of the periosteum Secondary ossification centers are located in the epiphyses
33
What tissues are involved in endochondral ossification
Begins with mesenchymal tissue transforming into a cartilage intermediate which is later replaced by bone and forms the remainder of the axial skeleton and the long bones
34
Left side of long bone
Proximal epiphysis Diaphysis Distal epiphysis
35
Right side of long bone
Articular cartilage Spongy bone Epiphyseal line Periosteum Medullary cavity lined by endosteum
36
Osteoporosis
Is a group of diseases in which bone resorption exceeds deposit Matrix remains normal, but bone mass declines Spongy bone of spine and neck of femur most susceptible Vertebral and hip fractures are common
37
Osteomalacia
Soft bones
38
Rickets
A lack of vitamin D or calcium in a child's diet bowed legs and deformation of the pelvis, skull and ribcage are common
39
Pagets disease
Disruption in normal remodeling Initially, old bone breaks down faster than new bone can be rebuilt later new bone is produced at a faster than normal rate more spongy bone Results in enlarged and deformed bones in one or more regions of the skeleton Cause unknown may be initiated by a virus
40
What are the functions of the bones
Support Protection Anchorage Mineral Storage Blood Cell Formation red bone marrow Storage of fats yellow marrow Hormone production osteocalcin
41
Hematopoiesis
Hematopoiesis is the process by which the body produces blood cells It occurs in the hematopoietic system which includes organs and tissues such as the bone marrow liver and spleen
42
Organic materials of compact bone
Organic Components 1/3 is osteoid ground substance proteoglycans and glycoproteins Collagen fibers provides flexibility and tensile strength
43
Inorganic materials of compact bone
Inorganic Components 2/3 of matrix Mineral Salts hydroxyapatite calcium phosphate crystals Provides hardness and compression resistance weight bearing strength
44
What's the difference between periosteum and endosteum
Periosteum and endosteum are both layers of tissue that cover bones The periosteum covers the outer surface of bones while the endosteum lines the inner surface of the medullary cavity
45
What are the compact bone parts and their functions
Osteoblasts: bone cells that produce new bone tissue Lamellae: layers of tissue that form concentric circles around the osteon Central canal: a tube-like passage that contains blood vessels and nerve fibers Lacunae: small spaces that contain bone cells osteocytes
46
What happens to a long bone as an individual reaches skeletal maturity
When an individual reaches skeletal maturity the growth of their long bones stops This happens because the cartilage in the epiphyseal plate which is the growth layer of a long bone is replaced by bone The chondrocytes in the epiphyseal plate divide during development and when they stop dividing the bone stops growing in length.
47
What are the different horomones involved in bone growth
Thyroid hormone Estrogen and testosterone