Exam 3 inflammatory blistering diseases Flashcards

1
Q

What are the hallmarks of HSV-1?

A

Above neck, mouth lesions, less recurrence than HSV-2

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2
Q

What are the hallmarks of HSV-2

A

genitalia STD, recurrent

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3
Q

What are the hallmarks of vericella (chicken pox)?

A

dew drops of a rose petal (chicken pox)

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4
Q

What are the hallmarks of herpes zoster?

A

Unilateral dermatome has many lesions

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5
Q

What are the hallmarks of impetigo?

A

honey-colored crusting

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6
Q

What are the hallmarks of bullous pemphigoid?

A

Tense blisters (don’t move much)

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7
Q

What is the disease associated with dermatitis herpetiformus?

A

celiac’s disease, gets worse with gluten

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8
Q

What is the hallmark of pemphigus vulgaris

A

flaccid blisters

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9
Q

What is the hallmark of porphyria cutanea tarda

A

hyperpigmentation

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10
Q

What do infections of HSV-1 and HSV-2 occur?

A

HSV-1 is in childhood, HSV2 is STD of adults

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11
Q

What is a specific treatment of HSV1

A

acycolvir (oral), famciclovir, valacyclovir, contagion prevention

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12
Q

How long does the varicella virus take to incubate?

A

14 days

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13
Q

What are the prodromes of varicella?

A

fever, chills, malaise, 2-3 days before onset of rash

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14
Q

What are major complications of varicella?

A

encephalitis, pneumonia, hepatitis, Reye’s syndrome, can become septic with secondary infections

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15
Q

What is the immunization schedule for varicella?

A

2 doses: 1st at 12-15 months then 2nd at 4-6 years. People over 13 years should get 2 doses 28 days apart

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16
Q

What is the prodrome of herpes zoster?

A

pain along nerve root up to 5 days prior to rash

17
Q

What else should you rule out with herpes zoster?

A

Immunosuppression (cancer, HIV, connective tissue disease

18
Q

What are the current treatments of herpes zoster?

A

acyclovir (PO, IV), prednisone

19
Q

What should you worry about with a herpes zoster outbreak on the face?

A

Infection of the eye leading to blindness

20
Q

How quickly should you treat herpes zoster to reduce post-herpetic neuralgia?

A

Treat within 48 hours

21
Q

What causes non-bullous impetigo?

A

Group A strep pyogenese (catalase-, Beta hemolytic) staph aureus (catalase+, coagulase+), mixed infection

22
Q

What causes bullous impetigo?

A

group II staph aureus (contains epidermolytic toxin)

23
Q

What’s more common, bullous or non-bullous impetigo?

A

non-bullous

24
Q

What is non-bullous impetigo?

A

single red macule or papule that becomes vesicle that erups and forms an erosion that dries to make honey-colored crust

25
Q

What is bullous impetigo?

A

Superficial vesicles that progress rapidly to flaccid bullae with sharp margins and no surrounding erythema, eruption leads to yellow crust with oozing

26
Q

Should you pop impetigo pustules?

A

NO

27
Q

Treatment of bullous impetigo?

A

Hygienic measures, topical antibiotics, oral antibiotics

28
Q

Name the different bullous diseases (all autoimmune)

A

Bullous pemphigoid, pemphigus vulgaris, dermatitis herpetiformis

29
Q

Describe bullous pemphigoid. treatment?

A

Tensile bullae on normal or erythematous skin; prednisone, topical cortisone

30
Q

Describe dermatitis herpetiformis. What disease is it associated with?

A

autoimmune condition with clusters of erythematous papules, pruritic and distributed symmetrically along extensor surfaces; Associated with Celiac’s

31
Q

Describe pemphigus vulgaris

A

flaccid blisters on head, trunk and intertriginous areas, Nikoslky sign

32
Q

What condition results in porphyria cutanea tarda?

A

deficiency in heme-synthesizing enzyme

33
Q

Describe porphyria cutanea tarda?

A

blistering of skin in sun-exposed areas, hyperpigmentation

34
Q

What are risk factors for porphyria cutanea tarda?

A

hepatitis C, hemochromatosis and alcoholism