Exam 4 Encephalitis/CNS Abscess Flashcards Preview

Q4 Clin Med III (GI) > Exam 4 Encephalitis/CNS Abscess > Flashcards

Flashcards in Exam 4 Encephalitis/CNS Abscess Deck (15):
1

Meningitis vs Encephalitis, primary difference?

Normal or abnormal brain fxn:

Menin = Normal fxn; have fever, HA, etc

Enceph = Altered mental state (AMS), seizures, motor/sensory deficits

2

Encephalitis is?

Primary infection?

Postinfection?

Acute inflamm of brain from Virus

Viral invasion of CNS w/ neuronal involvement,
Virus is identifiable by tissue cx

Immune response w/ neurons spared,
Can't identify virus

3

Encephalitis etiology? (3)

HSV 1: most C and most important to identify and treat (in temporal lobe)

Arbovirus/U travel-related (West Nile, St Louis, Eastern/Western)

Zoster, EBV, HIV, etc

4

Encephalitis presentation? (5)

HA
AMS
Seizures
Focal defects: hemiparesis, CNs, ↑DTR
PHOTOPHOBIA/NUCHAL RIGIDITY ARE RARE

5

Encephalitis labs? (4)

Imaging? (2)

Same (results will be same as Aseptic Meningitis if meningoencephalitis)
PCR for HSV/Enterovirus
CSF/Blood Cx for virus, bacteria, fungus, mycob
Brain Bx


CT/MRI = normal or abnormal
EEG = abnormal

6

Encephalitis tx? (2)

Acyclovir IV
Seizure prophy

7

Encephalitis prognosis?

Poor neuro recovery if diffuse edema or intractable seizures

HSV = Fatal w/o tx (14% die anyway), 24% get epilepsy

8

Cerebral Abscess is?

U caused by?

Focal infection of capsulized pus

Infection, trauma, surgery

9

Cerebral Abscess from infection: Direct route of spread? (6)

Otitis media
Mastoiditis
Meningitis
Sinusitis
Dental
Head trauma

10

Cerebral Abscess from infection: Hematogenous route of spread? (4)

Pulmonary
Skin
Intra-abdonminal
Pelvic

11

Cerebral Abscess etiology?

U bacteria:
Strep, Staph, G-, Anaerobes

Immigrants:
Parasites

12

Cerebral Abscess presentation? (7)

U non-specific
Unilat HA
Fever
Nuchal rigidity
AMS
Focal deficits
Seizure

13

Cerebral Abscess labs? (2)

CBC w/ diff
Blood Cx x2

14

Cerebral Abscess imaging?

MRI (study of choice) = Ring-enhanced lesion
Early -> poor demarcation, local edema, no necrosis
Late (>2wks) -> necrosis, liquefaction, fibrotic capsule

15

Cerebral Abscess tx?

CT-guided aspiration
ABX 4-8 wks