Exam #4 Vocab Flashcards

1
Q

resistance mutation

A

random gene change produces a gene causing resistance

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2
Q

natural selection

A

when the antibiotic is present (environment) bacteria with the resistance gene (genetic differences) survive and reproduce (difference in reproduction)

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3
Q

trade-off

A

when the antibiotic is absent (environment) bacteria with the resistance gene (genetic differences) reproduce more slowly than the susceptible bacteria (differences in reproduction)

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4
Q

penicillin

A

kills gram-positive bacteria by damaging peptidoglycan in the gram-positive and cell wall

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5
Q

penicillin-resistant bacteria

A

produce a protein that cuts penicillin molecules in half before they damage the cell wall

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6
Q

KPC gene

A

gives resistance to multiple antibiotics

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7
Q

virulence

A

the degree of damage caused by a pathogen to its host

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8
Q

physiology

A

study of internal organismic functioning, especially the physical and chemical aspects of function

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9
Q

homeostasis

A

maintenance of stable internal conditions

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10
Q

set “point”

A

the usually maintained homeostatic conditions

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11
Q

negative feedback

A

a “sensor” triggers a response by a physiological system that returns the conditions to the set point

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12
Q

positive feedback

A

a “sensor” triggers a response by a increase the deviation from the set point (amplifies until end point)

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13
Q

hematocrit

A

erythrocyte blood volume (percentage of blood)

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14
Q

anemia

A

low hematocrit

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15
Q

hypoglycemia

A

low blood sugar; brief hypoglycemia is normal after not eating for a while

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16
Q

hyperglycemia

A

high blood sugar; brief hyperglycemia is normal after carbohydrate consumption

17
Q

clinical hypoglycemia

A

pancreas cells “over-react” to high glucose, secrete too much insulin then the liver stores too much glucose causing hypoglycemia

18
Q

type 1 diabetes

A

insulin-producing pancreas cells are killed (usually during childhood), thus no insulin; cannot “direct” liver to store glucose or direct other cells to absorb and use glucose (hyperglycemic but cells starve)

19
Q

type 2 diabetes

A

liver cells have a reduced sensitivity to insulin; the liver does not respond well to insulin; this leaves blood glucose high (genetic predisposition, age, smoking, or being overweight make it more likely)

20
Q

compensation

A

when the carbonate buffer system and body systems keep blood PH near 7.4

21
Q

acidosis/ acidemia

A

blood ph <7.35; affects brain and muscles (twitching and confusion, eventually results in coma and death)

22
Q

respiratory acidosis/ acidemia

A

too much CO2 in blood (usually due to lung malfunction-can’t release CO2)

23
Q

metabolic acidosis/ acidemia

A

add or retain H+ (poisoning- add H+, diabetic acidosis- add H+, or kidney malfunction- can’t release H+)