Exam 5 Deck 8

Question 1

Drug to promote cellular growth

Answer 1

Somatotropin

Question 2

Drug to reduce growth hormone

Answer 2

Octreotide

Question 3

AE: somatotropin

Answer 3

Hyperglycemia

Question 4

AE Octrotide

Answer 4

Glucose dysregulation, GI upset

Question 5

Drug for reabsorbing water

Answer 5

Desmopressin

Question 6

Indication for Desmopressin

Answer 6

Diabetes insipidus, bed wetting (von willlerbrand’s)

Question 7

Indications for Octreotide

Answer 7

Tumor with growth hormone, other excessive GH

Question 8

AE of Desmopressin

Answer 8

Hyponateriam
(Water dilution inside

Question 9

Drug for thyroid hormone replacement

Answer 9

Levothyroxine
Treats hypothyroidism
Can cause hyperthyroidsim

Question 10

Indication to increase dose of levothyroxine

Answer 10

Elevated TSH

Question 11

Contra Indication for levothyroxine

Answer 11

Cardiovascular disease

Question 12

Drug to lower thyroid activity (Treat Grave’s disease)

Answer 12

Methimazole

Question 13

CI for methimazole

Answer 13

Immunocompromised

Question 14

Indication for Propythiouracil

Answer 14

Hyperthyroidism

Question 15

How Propylthiouracil prevents Thyroid stimulations

Answer 15

Prevents Iodine from being active

Question 16

Drugs to treat addisons disease

Answer 16

Hydrocortisone and Fludrocortisone

Question 17

MOA and AE of hydrocortisone

Answer 17

MOA: Gucocorticoid
AE: Cushing’s syndrome, Infection, glucose intolerance, osteoporosis, adrenal suppression, peptic ulcers

Question 18

MOA of fludrocortisone

Answer 18

Mineralcorticoid: promotes Na+ reabsorption
K+ and H+ excretion

Question 19

S/S of hypoglycemia

Answer 19

Sweating
Pallor
Hunger
Irritability
Lack of coordination
Sleepy
(Hangry)

Question 20

S/S of hyperglycemai

Answer 20

(Dry)
Dry mouth
Thirst
Headache
Blurred vision

Frequent urination
Weakness

Question 21

Normal range for serum glucose

Answer 21

70-110 mg/dL

Question 22

Test to measure 3 month glucose level

Answer 22

HbA1C

Question 23

LeARNinG(D)
Pneumonic

Answer 23

Rapid acting
Lispro, Aspart

Short acting
Regular (clear)

Intermediate acting
NPH

Long acting Gargine, Detemir

Question 24

Onset for rapid acting insulin (Lispro, Aspart)

Answer 24

15-30 min

Question 25

Onset short acting insulin (Regular)

Answer 25

30-60 minutes

Question 26

Onset for intermediate acting insulin (NPH)

Answer 26

60-120 min

Question 27

Onset for long acting insulin (Glargine, Detemir)

Answer 27

70 min

Question 28

Peak effect for rapid acting insulin (lispro, aspart)

Answer 28

30 min - 2.5 hrs

Question 29

Peak affect for short acting insulin (regular)

Answer 29

1-5 hrs

Question 30

Peak effect for intermediate acting insulin (NPH)

Answer 30

6-14 hrs

Question 31

Peak effect for long acting insulin (glargine, determir)

Answer 31

None

Question 32

Duration of action for rapid acting insulin (lispro, aspart)

Answer 32

3-6 hrs

Question 33

Duration of action of short acting insulin (regular)

Answer 33

6-10 hrs

Question 34

Duration of action for intermediate acting insulin (NPH)

Answer 34

16-24 hrs

Question 35

Duration of action for long acting insulin (Glargine, detemir)

Answer 35

18-24 hrs

Question 36

When to use rapid acting insulin (lispro, aspart)

Answer 36

Meals or acute hyperglycemia

Question 37

When to use short acting insulin (regular)

Answer 37

Meals/acute hyperglycemia

Question 38

When to use intermediate insulin (NPH)

Answer 38

Basal levels

Question 39

When to use long-acting insulin (Glargine, Detemir)

Answer 39

Basal insulin

Question 40

Drugs to use in Type II diabetes mellitus

Answer 40

Glyburide/glipizide Repaglinide Acarbose Canagliflozin Metformin

Question 41

When to use glucagon

Answer 41

Hypoglycemia, emergency treatment

Question 42

Treatments for Type II DM that can cause hypoglycemia

Answer 42

Repaglinide Glyburide/glipizide

Question 43

Type II DM meds that do not cause Hypoglycemia

Answer 43

Metformin Acarbose Canagliflozin Pramlintide

Question 44

Treatment options for Type I DM

Answer 44

Insulin

Question 45

MOA of met formin

Answer 45

Increases glucose uptake through increasing insulin sensitivity

Question 46

Adverse effects of metformin

Answer 46

Lactic acidosis GI upset, VB12 and folate deficiency

Question 47

MOA of glyburide and Repaglinide

Answer 47

Stimulates the pancreas to release insulin

Question 48

MOA and AE for Acarbose

Answer 48

MOA: Slows carbohydrate absorption AE: GI upset

Question 49

MOA and AE of Canagliflozin

Answer 49

MOA: Causes kidney to excrete glucose AE: Cystitis, candidiasis, polyuria, hypotension (Increased glucose in urine= more infection)