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0 Pharmacology > Exam 5 Module 9 > Flashcards

Exam 5 Module 9 Flashcards

(48 cards)

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1
Q

5 Cardiac rules for adminitering antihypertensive meds

A

• Change positions slowly - Prazosin (ai antagonist) hydralazine (vasodialators
• BP < 90/60 hold and call HCP
• HR < 60 hold and call HCP (beta blockers)
• NEVER abruptly stop Clonidine and beta blockers
•Daily weight. Call HCP if 2+lbs gain in a day of 5+lbs in a week.

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2
Q

Inotrope

A

Cardia force/contractility

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3
Q

Chronotrope

A

Heart rate (timinig)

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4
Q

Dromotrope

A

Cardiac conduction

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5
Q

1st dose phenomenone

A

Sudden/severe drop in BP with starting new med (A1 blockers - prazosin)
Syncope and LOC
HCP to Prevent falls

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6
Q

First line meds for Persons with African ancestry

A

Hydrochlorothiazide, diltiazem, verapamil, nifedipine, amlodipine

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7
Q

Non-selective beta blockers

A

Propranolol (caution in COPD and asthma)
Nadolol

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8
Q

Cardio selective beta blockers

A

B1 only
Atenolol
metoprolol
Esmolol

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9
Q

Reversal agents for heparin

A

Protamine

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10
Q

Reversal agent for warfarin

A

Vitamin K, Fresh frozen plasma

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11
Q

Antiplatelet medications

A

Asprin
Clopidogrel
Abciximab
Dipyridamole

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12
Q

Anticoagulant medications

A

Warfarin
Heparin
Enoxaparin
Rivaroxaban
Dabigatran
Fondaparinux

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13
Q

Thrombolytics medications

A

Alteplase

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14
Q

Difference between antiplatelet and anticoagulants

A

Antiplatelet inhibit aggregation, anticoagulant block cascade

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15
Q

MOA and AE of Asprin

A

MOA: reduce # of platelets
AE: reyes syndrome ( kids under 19)

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16
Q

Indication and class for Clopidogrel

A

Class: antiplatelet
I: stroke, Stent

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17
Q

Heparin monitoring for

A

aPPT, and CBC (therapeutic monitoring )

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18
Q

Indication for Heparin

A

DVT (and prophylaxis of), PE, NSTEMI/STEMI

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19
Q

Class and application Enoxaparin

A

Class: anticoagulant
Application: SubQ » can use at home

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20
Q

AE for enoxapaparin

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A

Bruising/bleeding

21
Q

Warfarin onset

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A

3-4 days, requires bridging med

22
Q

Warfarin MOA

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A

Anticoagulant: Inhibits intrinsic factors II, VII, IX, X (vitamin K dependent

23
Q

Warfarin monitor

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A

INR/PT, Dietary changes in Vitamin K

24
Q

Contra indications of warfarin

25
Indication and route of dabigatran
I: prohylaxis of embolism (stroke). Bridge to warfarin Route: oral
26
MOA and monitor for Rivaroxaban
MOA: Inhibits factor XA Monitor CBC
27
Fondaparinux Indication
DVT, PE. Post operation.
28
MOA, Contraindication, Alteplase
MOA: Thrombolytic, dissolves clots CI: History of stroke in last 3 months (interfere with healing) Blooding, thrombocytopenia, hyertension
29
Hematopoietic growth factors
Erythropoietin Fligrastim Oprelvekin
30
Indication, MOA Erythropoietin
I: severe anemia MOA: Produce more RBC (from bone marrow)
31
MOA, CI, and AE for fligrastim
MOA: Produce neutrophils CI: Chemo w/n 24hrs AE: splenomegaly
32
MOA Oprelvekin AE
MOA: increase platelets AE: fluid retention
33
Indication and AE for Packed red blood cells
I: Severe anemia AE: Hyperkalemia
34
Common AE for blood blood products (minus albumin)
Allergic response, anaphylaxis, hemolytic reaction, febrile non-hemolytic reaction, sepsis
35
Indication for whole blood
Acute loss, dehydration
36
Indication and AE for platelet concentrate
I: thrombocytopenia AE: febrile nonhemolytic
37
Indication and AE for Fresh frozen plasma
I: Burns, blood loss, reverse warfarin, intravascular coagulation AE: circulatory overload
38
Indication and AE for Albumin
I: LIver cirrhosis, adult respiratory distress AE: Fluid overload, pulmonary edema
39
Indication and AE for Apheresed granulocytes
I: nuetropenia, neonatal sepsis, infection AE: circulatory overload
40
MOA, Indication for prazosin/doxazosin
MOA: Alpha 1 blocker I: Hypertension & BPH (raynauds)
41
MOA, I, CI, Propranolol
Non-selective beta blocker I: post MI CI: COPD/Asthma
42
MOA, I Metoprolol
Cardio selective (Beta 1) antagonist I: hypertension
43
MOA, AE hydralazine
MOA: vasodilation AE: hypotension, bradycardia *edema*
44
Nitroprusside monitor, I
Cyanide poisoning I: Congestive heart failure
45
MOA: Eplerenone
MOA: aldosterone inhibitor, will increase potassium
46
MOA, I Aliskiren
MOA: Renin inhibitor I: hypertension
47
Clonidine MOA, AE
MOA: A2 agonist AE: brady-, dizziness, dry-mouth, sedation
48
Antihypertensive medications (8)
Prazosin Propranolol Metoprolol Hydralazine Nitroprusside Eplerenone Aliskiren Clonidine

0 Pharmacology (8 decks)

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