Exam #5: Single Gene Disorders Flashcards Preview

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Flashcards in Exam #5: Single Gene Disorders Deck (37)
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31

Fitness

Chance of reproduction

32

Mutation Hotspot

- Chromosomal region where mutations occur frequently
- CG dinucleotide repeat is common example
- Cytosine is methylated to methylcytosine & deaminated, yielding tymine

33

Ova Mutations

Nondisjunction

34

Sperm Mutations

Point Mutation

35

X-linked Recessive Pedigree

- No father-son transmission
- Affected boys usually have unaffected parents
- Males are affected more frequently than girls

36

X-Linked Dominant Pedigree

- Male transmits to all of his daughters
- Female transmits to half of children regardless of sex

37

Mitochondrial Inheritance Pedigree

Mothers pass to all of their children