exam III Flashcards

(68 cards)

1
Q

glycolysis

A

“sugar splitting”, 6 ATP

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2
Q

glycolysis location

A

cytosol

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3
Q

preparatory reaction

A

converts glycolysis products into C2 acetyl group and CO2 given off, occurs twice per glucose molecule, 6 ATP

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4
Q

preparatory reaction location

A

entering mitochrondrion

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5
Q

citric acid cycle

A

substrate-level ATP synthesis, produces both NADH and FADH2, 4 ATP

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6
Q

citric acid cycle location

A

inside mitochondrion (matrix)

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7
Q

oxidative phosphorylation

A

exchanges high energy electrons carried by NADH+FADH2 for ATP

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8
Q

2 chunks of oxidative phosphorylation

A

electron transport chain + chemiosmosis

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9
Q

oxidative phosphorylation location

A

inside mitochondrion (inner membrane)

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10
Q

ATPs per NADH and FADH2

A

3 per NADH, 2 per FADH2

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11
Q

cellular respiration makes ___ ATP

A

~38

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12
Q

4 cellular respiration steps

A

glycolysis, prep reaction, citric acid cycle, oxidative phosphorylation

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13
Q

aerobic respiration step

A

oxidative phosphorylation

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14
Q

two steps of cellular respiration that make CO2

A

citric acid cycle + oxidative phosphorylation

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15
Q

not enough oxygen? need…

A

fermentation

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16
Q

if O2 is in plenty, 1 glucose =

A

38 ATP

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17
Q

where is energy in glucose?

A

in electrons of its hydrogen ions

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18
Q

fermentation allows

A

to keep creating NAD+ and continue glycolysis in absence of oxygen

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19
Q

types of fermentation

A

lactic acid fermentation + ethanol fermentation

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20
Q

cell cycle

A

repeating of cell division

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21
Q

cell theory

A

all cells from cells

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22
Q

apoptosis

A

“programmed cell death”

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23
Q

prophase

A

centrosomes separate, chromatin condenses, spindles elongate inside nucleus

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24
Q

prometaphase

A

nuclear envelope mostly gone, centrosomes at poles pushed by fibers

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25
metaphase
chromosomes at center, pulled by kinetochores, attached to spindle
26
anaphase
sister chromatids separate, the centromere splits
27
telophase
chromosomes decondense, nuclear envelope reappears
28
interphase phases
G0, S, G2
29
centrosome
brain of cytoskeleton
30
histones
made of protein, help organize DNA
31
nucleosome made up of
DNA + 8 histones
32
states of DNA packing
euchromatin (loose, uncondensed, unorganized, active) + heterochromatin (condensed + inactive)
33
fibroplast
skin stem cell
34
cancer critical genes
encode proteins that help to control the rate of cell division (ex: ras)
35
proto-oncogenes (normal genes)
normally speed up cell cycle, encode “gas pedal” machinery, if mutated, could become an oncogene [causes cancer]
36
tumor suppressor genes
“brakes” of cell cycle ~ normally, If mutated, fail to stop/slow cell cycle when it needs to
37
ras
protein, proto-oncogene : if mutated, “stuck gas pedal”
38
p53
tumor suppressor gene : if low O2, force cell into apoptosis
39
angiogenesis
growth of new blood vessels (key step in growth of tumor) – triggered by VEGF
40
binary fission
“ prokaryotic cell cycle “
41
meiosis purpose
make eggs and sperm (gametes), reduces ploidy, daughter cells not identical
42
meiosis ploidy reduction
diploid --> haploid
43
fertilizatoin __ ploidy
doubles
44
meiosis ___ ploidy
halves
45
ploidy
number of potential versions
46
diploid
two versions of each chromosome (“tell the same story”)
47
homologous pair
two chromosomes containing different versions of the same genes (alleles)
48
independent assortment
random orientation of each tetrad (meiosis I)
49
2^? = x possible outcomes
2^number of chromosomes
50
crossing over can only happen with...
members of homologous pair
51
G1 / G2
cell is growing
52
G2
DNA + centrosomes duplicated
53
S
synthesis of DNA , copying its DNA
54
dehydrogenase enzyme
pulls H out of glucose
55
NAD+
coenzyme partner of dehydrogenase, accepts electrons of 2 Hs
56
NADH
acts as "truck" carrying 2 electrons to energy-harvesting destinations
57
electron transport chain
spends NADH + FADH2 "fuel" to create a proton gradient, reduces molecular oxygen to water
58
chemiosmosis
active transport of proteins against gradient, shot back into matrix by ATP synthase
59
fermentation yields __ ATP per glucose
2
60
fermenation is _ + _
glycolysis + a NADH recycling
61
M checkpoint
chromosomes on spindle?
62
G1 checkpoint
DNA ok?
63
G2 checkpoint
DNA replicated?
64
the eukaryotic chromosome
location of cell's genetic information
65
chromatin
DNA + scaffolding proteins
66
cytokinesis
division of cytoplasm into two, copies of chromosomes as far apart as possible
67
crossing over occurs in...
prophase I of meiosis I
68
chiasma
structure that holds together homologues during crossing-over