Exam Qs Flashcards

1
Q

name cells that secerete histamine in stomach

A

ECF-like cells

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2
Q

Symptoms of TACS, PACS, lacunar

A

TACS - HHHH - all - hemiparesis, hemisensory loss, hemianopia, higher cerebral dysfunction
PACS - 2 of HHH or just higher cerebral
lacunar - motor or sensory or motor-sensory or ataxic

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3
Q

what is higher cererbal dysfunction

A

lack of attention, language disorder, visiospatial disorder, memory, personality change, apraxia

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4
Q

function of temporal lobe and parietal lobe

A

temporal - memory, language (wernickes in dominant), hearing
parietal - dom - logic, calculation, speech, recognising objects, sensory integration
non dom - visiospatial (hemineglect), arts,

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5
Q

symptoms of temporal and parietal lobe stroke

A

dom parietal - problems with calc, agnosia (cant recognise objects), aphasia
non dom parietal - problems drawing, hemineglect
temporal - impaired memory, wernickes apahasia in dominant, selective memory,

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6
Q

how is the sleep cycle regualted

A

hypothalamus inhibits RAS for sleep. RAS activates thalamus to wake up

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7
Q

explain the process behind decerebrate posturing

A

corticospinal inhibits reticulo spinal but damage to corticospinal results in decerebrate prosturing.

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8
Q

explain process behind decorticate posturing

A

damage to corticospinal results in no inhibition. ruberospinal flexes upper limbs and reticulospinal extends lower.

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9
Q

explain how acetyl coa makes colesterol or ketone bodies

A

amount of insulin decides. With insulin goes to cholesterol. without goes to ketone bodies.

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10
Q

what is hematocrit

A

% of RBCs in blood

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11
Q

what is aphonia, aphasia, disarthria

A

aphasia - language disorder
aphonia - no voice
disarthria - unclear articulation
aphonia and disarthria are types of aphasia

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12
Q

commonest way for infection to spread to retropharyngeal space

A

teeth infection

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13
Q

pattern of inheritance of familial hypercholesterolemia

A

auto dominant

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14
Q

inflammatory markers in blood

A

CRP, WBCs

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15
Q

what layer is atheromas formed in

A

tunica intima

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16
Q

name a ketone body

A

beta-hydroxybuyrate

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17
Q

what would u see in a blood test indicating neural tube dysfunction

A

increased alpha-fetoprotein

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18
Q

what does RA and OA affet

A

RA - synovial membrane - thickens and inflames

OA - articular hyaline cartilage. Sclerosis and osteophytes

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19
Q

how does anemia affect blood flow

A

flow murmur

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20
Q

ions in vomit. is gastric juice hypertonic, isotonic or hypotonic.

A

H, cl, K

gastric juice is hypertonic

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21
Q

symptoms of chronic uncontrolled asthma

A

reduced growth and chest wall deformities

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22
Q

histology of acute and chronic asthma

A

acute - oedema, mucus hypersecertion, bronchspasm

chronic - SM hypertrophy, mucus gland hyperplasia

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23
Q

where does oesophagus constrict

A

at start, through diaphragm, and at aortic arch

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24
Q

what is achalasia

A

lower oesophageal SM not relaxing

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25
how test for hematuria
dip stick, microscopy urin
26
swellings in testes
hematocoele, varicocoele, hydrocoele, spermatocoele, torsion
27
how test testicular swelling
USS, MRI
28
hhistology of malignancy
poor differentiation, pleimorphic, increased mitotic figures
29
what is basal ganglia made of and functions
made of striatum and globus pallidus | functions to determine amplitude and velocity of movement and inhibit unwatned movements
30
how test female ovulation
plasma prog at day 21
31
what could pleuritic chest pain be
pneumonia, PE, TB, pneumothorax
32
cofactors of erythropoiesis
b12 and folate
33
antenatal tests
USS, dipstick (protein for pre eclampsia), BP, sugars (gestational diabetes), bloods (iron and folate)
34
clinical signs of hypertension
headaches, blurred vision, epistaxis
35
what is a pseudocyst and where would it happen
no epithelial cells | happens due to acute pancreatitis in lesser sac
36
enzyme that conjugates bilirub
glucuronyl transferase
37
signs of increased ICP
vomiting, altered consciousness, eye palsies (abducens), papilloedema
38
condition of CSF coming out of ear
CSF otorrhoea
39
nerves of femoral, sciatic and obturator
femoral and obturator - L2-L4 | sciatic - L5-S3
40
why is shoulder joint not likely to be dislocated superiorly
acromioclavicular joint in way
41
signs of HF
increased JVP, oedema, pulmonary crackles, peripheral cyanosis
42
how would you test blood flow through heart
echocardiogram
43
area of bladder prone to stretching
trigone of bladder
44
what is intention to treat analysis. why is it gud
everyone included if they adhered or dropped out. mirrors actual clinical practice
45
receptors that vasodilate arteries
skeletal and coronary - b1, NA | everywhere else - NA acts on alpha1
46
clinical signs of hyperthyroidism
hyperreflexia, tachycardia
47
how does cell recognise viral infection and clear it
MHC1 recognised by CD8 cells
48
fibrocytstic changes in breast
fibrosis, epithelial hyperplasia, cysts
49
what damaged in ulcer of posterior wall of stomach
splenic artery, pancreas
50
what happens to femur in dislocation and fracture and why
dislocation - medial rotation due to gluteal pull | fracture - external rotation due to illiopsoas pull
51
what is the supinator reflex nerves
c5-6
52
how measure true and apparent leg length
true - greater trochanter to medial malleolus | apparent - ASIS to medial malleolus
53
what substances induce pyrexia and where do they act
TNF-alpha and IL-1 on hypothalamus
54
what is a fibroid
benign tumour of uterine SM
55
daily expenditure of 80kg male
12kJ
56
inflammatory process mediators
histamine, prostaglandins, leukotrienes, thromboxane a2
57
causes of polyhydriamnos
duodenal atresia, oesophageal atresia
58
how is amniotic fluid produced in early and late stage
early - transudate across fetal skin and amnion | late - fetal urine in the kidneys
59
blood supply of thalamus, internal capsule, pons, hypothalamus, medulla
thalamus - post cerebral internal capsule - mid cerebral pons - pontine arteries hypothalamus - anterior and posterior cerebral medulla - ant spinal. post inf cerebellum
60
risk factors of breast cancer
breast feeding (protective), HRT/COCP, menopause age
61
give examples of apocrine and holocrine sweat gland
apocrine - arm pits, groin sweat glands. Mammory glands | holocrine - sebaceous glands (hair), tarsal glands
62
when is tamiflu affective
within 48 hrs of symptoms appearing
63
what is status asthmaticus
64
what is granuloma and granulation tissue
granuloma - foreign body walled off | granulation tissue - healing
65
what does proline and lysine do to collagen
increase strength and stability
66
what is histological features of type 1 and 2 muscle fibres
type 1 - slow, thinner diameter, redder (myoglobin), fatigue resistant, aerobic (more mitochondria??)
67
what is gene penetrance
how likely gene will manifest itself
68
give cancer metastases to bone, liver, brain, lungs
lungs - Real Hardcore Cancers Fill Both My lungs - RCC, HCC, Choriocarcinoma, Follicular thyroid, breast, melanoma Brain - Cancer: Some Love Killing Brain Glia - Skin, lungs, Kidneys, breast, GI Bone - PB-KTL - prostate, breast, kidney, thyroid, lung Liver - Cancer Sometimes Penetrates Benign Liver - colon, stomach, pancreas, breast, lung
69
how carbimazole works
prevents iodinisation of thyroglobulin
70
what happens to lactate
to glucose by liver | or to pyruvate by muscle, heart, brain
71
Give SAN and cardiac AP
SAN - funny current, calcium in, potassium out cardiac - Na in, K+ and Cl out, calcium in and K out, K out.
72
commonest fracture area of scaphoid
waist of scaphoid
73
what parts of brachial plexus under clavicle
branches and cord
74
causes of aortic stenosis
age related calcification, rheumatic fever
75
Drug for diarrhoea and MoA?
Loperamide - opioid