Exam V: Drugs of Abuse Flashcards Preview

Pharmacology > Exam V: Drugs of Abuse > Flashcards

Flashcards in Exam V: Drugs of Abuse Deck (10):
1

Definitions of Addiction, Dependence, Tolerance, and Withdrawal

Addiction: organism engages in compulsive and reinforcing/rewarding behavior, but loses control of limiting intake

Dependence: when an organism normally only in the presence of the drug, and a physical disturbance manifests when drug is removed (withdrawal)

Tolerance: when an organism no longer responds to a drug, and must have higher doses to obtain effectiveness

2

Which area of the brain does cocaine bind that causes pacing, nail biting, and scratching?

Caudate nucleus

3

10 mg IV morphine every 3 hours is equivalent to how much methadone?

10 mg IV methadone every 6 hours

4

Mydriasis is a short term pharmacological affect of which drug?

Morphine

5

Patient comes to ER with narcotic overdose. Which drug do you give them?

Naxolone

6

What is a naturally occurring opiate analgesic-like substances in the brain?

Endorphins

7

Morphine exerts analgesic action on which type of receptors?

Mu

8

Meperidine affects which type of receptors in the limbic system?

Sigma

9

5 mg IV heroine is equivalent to how much methadone?

20 mg oral methadone

10

VTA neurons contain what NT?

Dopamine