ezetimibe Flashcards
1
Q
main indication
A
Hypercholesterolaemia - used in combination with statins when statins alone are not enough, or if statins not tolerated
2
Q
mechanism of action
A
Inhibits NPC1L1 transport protein in enterocytes of the duodenum, reducing the absorption of cholesterol
3
Q
contraindications and cautions
A
Contraindicated in breast feeding females
4
Q
administration
A
PO
5
Q
adverse effects
A
Few adverse effects, but diarrhoea, abdominal pain and headache may occur
