f, lec (g lamblia) Flashcards

(47 cards)

1
Q

g lamblia causes

A

epidemic and endemic diarrhea

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2
Q

g lamblia AKA

A

giardia intestinalis, g duodenalis, lamblia duodenalis or L intestinalis

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3
Q

first discovered by

A

anton van leeuwenhock

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4
Q

first described by

A

Lambl

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5
Q

lambl called it

A

cerconomas intestinalis

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6
Q

was renamed by

A

stiles

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7
Q

disease is called

A

giardiasis or lambliasis

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8
Q

asexual cycle includes

A

binucleated flagellated troph and quadrinucleated infective cyst

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9
Q

parasite are classified as

A

genotype A and genotype B

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10
Q

troph is what shaped

A

pyriform or teardrop shaped, pointed posterior

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11
Q

pair of nuclei in troph is found where

A

each side of midline

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12
Q

midline is called

A

axostyle

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13
Q

dorsal side of troph

A

convex

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14
Q

ventral side of troph is

A

concave with large adhesive disk

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15
Q

motion of troph

A

erratic tumbling of four flagella

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16
Q

motility of g lamblia is called

A

falling leaf or corkscrew motility

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17
Q

troph of g lamblia is divided by

A

longitudinal binary fission

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18
Q

troph, reason for resistance to intestinal proteinases

A

variant specific surface proteins

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19
Q

troph of g lamblia can be found where

A

diarrheic stool

20
Q

g lamblia is also described as

A

old mans eye glasses

21
Q

young cyst has how many nuclei

22
Q

mature cyst has how many nuclei

23
Q

characterized by retracted flagella

24
Q

flagella retracts to where?

25
cyst is transmitted by
contaminated hand, mouth, food
26
infective stage
mature cyst
27
transmission
ingestion
28
when cyst is ingested where is it found
duodenum
29
ability to cause disease can be traced to its ability to
alter mucosal intestinal cells once its attached to the apical portion of the enterocyte via adhesive disk
30
attachement is influenced by
temp and pH
31
temp for adhesion
maximal at body temp
32
ph for adhesion
7.8 to 8.2
33
produced by the parasite which when activated by duodenal secretions can also facilitate adhesion
lectin
34
another factor for virulence aside from lectin
can rearrange cytoskeleton
35
rearrangement of cytoskeleton can cause
enterocyte apoptosis
36
cases of asymptomatic
50%
37
excessive flatus caused by acute causes leads to what odor
rotten egg
38
chronic infection is characterized by
steatorrhea
39
diagnosis
DFS, duodeno-jejunal aspiration or biopsy, entero test (troph), antigen detection test, immunofluorescence test
40
gived higher percentage of positive findings
duodeno-jejunal aspiration or biopsy
41
accurate, inexpensive option for diagnosis
entero test
42
entero test, string is inside for how long
6-8hrs
43
gold standard in diagnosis of g lamblia
direct fluorescent antibody assays
44
treatment
oral metronidazole
45
alternative drugs
tinidazole, furazolidone, quinacrine, paramomycin
46
giardiasis is also called
gay bowel syndrome
47
t or f: g lamblia is zoonotic
true