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Flashcards in Fats + Exercise Deck (17):
1

fat distribution in body

more than 50x the energy of carbs
majority in adipose tissue then intra muscular triglycerides + plasma FFA

2

How and where are fats metabolized during ex.

by mitochondria in skeletal muscle
FAs released into circulation, some reesterfied + transported to tissues

3

how are circulating plasma lipoproteins + intramuscular triglycerides broken down

circulating- lipoprotein lipase breaks into FAs

intra- split by hormone sensitive lipase + transported to mito

4

limits to fat oxidation

-lipolysis in adiposytes
-removal of FAs from fat cells
-transport of fat by blood
-transport of FA into muscle/mitocondria
ox. of FAs in the b-oxidation path + TCA cycle

5

what does lipolysis of adiposytes depend on

Horomone sensitive lipase
conversion of inactive HSL to active HSL depending on the sympathetic nervous system + circulating epinephrine

6

removal of FAs and what are they transported by

-blood flow to adipose tissue
-albumin conc in blood
-number of binding sites for FAs on albumin

7

Transport of FA into muscle cells (what are the carrier pro.)

-specific carrier pro. transport FAs into muscles
-responsible for transport of most FAs across sarcolemma
-muscle contactions increase membrane FAT/ CD36

8

what type of muscle fibre has more intramuscular triacyclglyerics content and where r they located

type 1 has more
located next to mitochondria for immediate energy (elites)

9

transport of FAs into mitochondria and how does it happen/ what facilitates it

FA’s in the cytoplasm activated by acyl-coA synthase to form activated FA

activated FA then used to synthesize IMTG and bound to carotene

10

Caretine palmitoyl transferase I/II goes thru which membranes

I- thru outer
II- thru inner membrane

11

B oxidation dependent on

activity of enzymes
conc. of intermediates
presence of oxygen

12

Fat as fuel during exercise what happens(adaptations)

rate of lipolysis + rate of FA released increases
blood flow to adipose tissue increases
rate of reesterfication decreases
first 15 mins plasma FA decreases since uptake is high

13

what type of fat oxidation at low (25%), mod (65) and high (85)-

low- most oxidized from plasma FA

mod- FA contribution decreases, IMTG increases

High- fat oxidation decreases, decreased BF to adipose

14

endurance training on fat oxidation

-creates greater use of fat
-increased mitochondrial density
-increased capillary density (enhances FA delivery)
-increased FA transporters

15

effects of fasting and how is performance affected at high and low intensities

increased catocolamines
increased lipolysis
performance unaffected at low, decreased at high

16

short terms effects of high fat diets and effect on performance

impair fatigue resistance
decrease muscle glycogen
increase plasma FA +glycerol
no change/decreased performance cuz of fatigue

17

long term effects of high fat diets

lower carb utilization, higher fat utilization