FCE, ANNPE and HNPE

Question 1

Hamilton, VCOT, 2014:

1. Are dogs with HNPE more or less likely to present with signs of severe tetraparesis/tetraplegia compared with other compressive cervical myelopathies?
2. Most common sites of HNPE?

Answer 1

Hamilton, VCOT, 2014:

1. HNPE more likely to have severe tetraparesis/tetraplegia
2. C3/4 and C4/5

Question 2

Fenn, JAVMA, 2016:

1. Most common neurolocalization for ANNPE vs FCE?
2. Spinal hyperesthesia is more likely with ANNPE or FCE?
3. Fecal incontinence is more likely with ANNPE or FCE?

Answer 2

Fenn, JAVMA, 2016:

1. ANNPE: C1-5
   FCE: L4-S3
2. Spinal hyperesthesia more likely with ANNPE
3. Fecal incontinence more likely with FCE

Question 3

Specchi, JAVMA, 2016:

Describe the intramedullary hyperintensity on T2W FSE MRI images in ANNPE vs FCE?

Answer 3

Specchi, JAVMA, 2016:

ANNPE: non-longitudinal direction (oblique or vertical)
FCE: longitudinal, longer

Question 4

Nessler, JVIM, 2018:

1. Most common sites of HNPE?
2. What is the correlation between ratio of length of intramedullary hyperintensity to length of C3 with time to functional recovery and short-term survival in dogs with HNPE?
3. What % achieved functional recovery from HNPE?

Answer 4

Nessler, JVIM, 2018:

1. C4/5 (44%), C3/4 (22%)
2. Smaller ratio = shorter time to functional recovery and better short-term survival
3. 92% achieved functional recovery