February 1, 2016 - Rheumatic Fever Flashcards Preview

COURSE 3 > February 1, 2016 - Rheumatic Fever > Flashcards

Flashcards in February 1, 2016 - Rheumatic Fever Deck (11):

Acute Rheumatic Fever

Is an inflammatory disease that can involve the heart, joints, skin, and brain.

The disease typically develops two to four weeks after a throat infection.

Signs and symptoms include fever, multiple painful joints, and rash.


Acute Strep Pharyngitis

Tonsils are often inflamed and have exudate.

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Pathophysiology of Rheumatic Fever

Antibodies which the immune system generates against the highly antigenic M protein may cross-react with cardiac myofibers.


Epidemiology of Rheumatic Fever

Mainly seen in developing countries.

Almost eliminated in North America.


Jones Criteria

Used to help diagnose rheumatic fever. You need at least 2 major criteria and one minor criteria to diagnose as rheumatic fever.

MAJOR CRITERIA ----- Polyarthritis, carditis, subcutaneous nodules, erythema marginatum, or Sydenham's chorea.

MINOR CRITERIA ----- Fever, arthralgia, raised ESR or CRP, leukocytosis, ECG showing features of heart block, or a previous episode of rheumatic fever.


Sydenham's Chorea

Is a disorder characterized by rapid, uncoordinated jerking movements affecting the face, hands and feet.

Occurs in 20-30% of patients with acute rheumatic fever.


Erythema Marginatum

Is a type of erythema involving pink rings on the torso and inner surfaces of the limbs which come and go.

Occurs in about 5% of patients with rheumatic fever.

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Right-Sided Valve Involvement

Can be affected, however far less commonly.

This is because it is a low pressure system with fewer Eddy Currents for antibodies or bacteria to be deposited along the valves.


Rheumatic Fever and the Mitral Valve

Leaflet thickening

Shortened chordae tendinae

Commissural fusion


Restricted leaflet motion


Rheumatic Fever and the Aortic Valve

♦ Will never occur without mitral valve involvement ♦


Leaflet thickening

Commissural fusion


Restricted leaflet motion


Treatment for Group A Strep

Penicillin G

Penicillin V


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