female repro Flashcards

(38 cards)

1
Q

ovaries

A

paired
- germinal/ovarian surface epithelium (source of ovarian carcinomas)

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2
Q

ovarian cortex

A

contains ovarian follicles

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3
Q

ovarian medulla

A

contains blood vessels, nerves, etc

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4
Q

ovarian cycle

A

follicular phase day 1-14
ovulation day ~14
luteal phase day 14-28

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5
Q

follicular phase

A

primordial follicle matures to graafian with FSH

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6
Q

primordial follicle

A

oocyte
- squamous follicular cells

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7
Q

primary follicle, unilaminar

A

oocyte
- cuboidal follicular cells

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8
Q

primary follicle, multilaminar

A

oocyte
- granulosa cells
- zona pellucida
- theca interna

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9
Q

granulosa cells

A

come from proliferating follicular cells

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10
Q

zona pellucida

A

glycoprotein layer separating oocyte and granulosa cells
- prevents polyspermy

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11
Q

theca interna

A

surrounds follicle
- estrogen production

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12
Q

follicular phase hormone production

A

cholesterol delivered to thecal cells by blood vessel
- converted to progesterone
- converted to androstenedione
- crosses basement membrane to granulosa cell
- aromatase in granulosa cells converts it to estrogen
- goes back to blood

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13
Q

secondary follicle

A

oocyte
- granulosa cells
- zona pellucida
- theca interna
- antrum (fluid filled chamber)

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14
Q

graafian follicle

A

oocyte
- granulosa cells
- zona pellucida
- theca interna
- antrum
- corona radiata

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15
Q

corona radiata

A

granulosa cells surrounding oocyte
- nourish after ovulation

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16
Q

ovulation

A

LH surge from ant pituitary
- egg released from ovary

17
Q

luteal phase, no fertilization

A

corpus luteum of menstruation producing estrogen (GL and TL cells)
- 2 weeks no fertilization, corpus luteam degenerates into scar tissue (corpus albicans)
- progesterone and estrogen maintain uterine lining

18
Q

granulosa lutein cells

A

modified granulosa cells
- produce most progesterone, convert androstenedione -> estrogen

19
Q

theca lutein cells

A

modified theca interna cells
- produce progesterone + androstenedione

20
Q

luteal phase hormone production

A

cholesterol enters TL and GL cells from blood
- converted to progesterone in both cells
- progesterone -> androstenedione in TL cell
- androstenedione travels to GL cell where aromatase converts it to estrogen.
- estrogen goes to bloodstream

21
Q

luteal phase, fertilization

A

corpus luteum of pregnancy is maintained for 8-12 weeks by embryonic human chorionic gonadotropin (hCG)
- at 8-12 weeks:
- placenta takes over production of progesterone
- corpus luteum degrades into scar tissue (corpus albicans)

22
Q

uterus

A

3 main parts:
- fundas
- body
- cervix

3 layers in wall:
- endometrium
- myometrium
- serosa/adventitia

23
Q

fundas

A

rounded area above oviducts

24
Q

body

A

broad area on sides

25
cervix
inferior canal
26
endometrium
inner, mucosal lining
27
myometrium
middle muscular
28
serosa/adventitia (uterus)
outer CT
29
days 1-4 endometrium
- thin endometrium - no lining epithelium - only glandular base and straight arteries
30
days 4-14 endometrium
- thicken to 2-3mm (E) - glands grow - helical arteries regrow
31
days 14-28 endometrium
- endometrium at its thickest (5mm) - glands grow, spiral, and secrete nutrients (progesterone) - helical arteries continue growth
32
mammary gland
15-20 exocrine glands (compound tubuloalveolar) epithelium: parenchyma CT: stroma
33
resting mammary gland
ducts + lobules
34
parenchyma of resting mammary gland
- terminal ductules composed of simple cuboidal epi - surrounding myoepithelial cells are contractile
35
lactating mammary gland during pregnancy
terminal ductules branch, grow, and develop alveoli
36
lactating mammary gland after birth
alveolar cells stimulated to produce milk - myoepithelial contraction for milk ejection
37
prolactin
stimulates alveolar cells to prod milk after pregnancy
38
oxytocin
released when infant suckles, stimulates myoepithelial contraction