Final - 2 MOA Flashcards
(51 cards)
1
Q
- increase myocardiacl contractility = increase CO
- cardiogenic shock
A
dobutamine
2
Q
- increase osmolality of filtrate in renal tubuled
- increase osmolality of plasma
- TBI & glaucoma
A
mannitol
3
Q
are calcium channel blockers nodal or non-nodal
A
NODAL
4
Q
which Ca+ channel blocker is more for atrial dysrhythmias
A
diltiazem
5
Q
- Major depression
- Panic disorder
- General anxiety
- Social anxiety
A
venlaxafine
6
Q
- block Na+ in ditabl tubule
- mild to moderate HTN
- edema
- reduces BP 10-20
- decreases excretion of calcium
A
hydrochlorothiazide
7
Q
- All seizures except absence seizures
- Class 1B antidysrhythmics (off-label: V. tach)
A
phenytoin
8
Q
- Drug of choice for life-threatening status epilepticus
- Antianxiety
- Sedative-hypnotic
- Anti-seizure agent
A
lorazepam
9
Q
- relaxas arterial smooth muscle, reduces afterload
- low to midd 200 BP
- fast acting
- metabolized into cyanide
A
nitroprusside sodium
10
Q
- Major depressive disorder
- Neuropathic pain
- Fibromylagia
- Anxiety
- Stress urinary incontinence
A
duloxetine
11
Q
- Dopamine system stabilizer
- Positive & negative symptoms of schizo c bipolar
- Add-on for major depression
- Irritability c autism
A
aripiprazole
12
Q
Increases synthesis of serotonin
Management of bipolar disorder
A
lithium carbonate
13
Q
- Beta 1 adrenergic blocker
* **-rapid correction of SVTs
A
esmolol
14
Q
- first thrombolytic that was approved
- 2nd line thrombolytics
- obtained from beta-hemolytic streptococci & is less firbin speciic
A
streptokinase
15
Q
- increase BP
- increase myocardial contractility
- hypovolemia (must also give volume expanders)
- cardiogenic shock
A
dopamine
16
Q
- non-nodal
- phase 3
- delay repolarization & prolong refractory period = increase QT interval
- reduce automaticity = correct dysrhythmias
A
potassium channel blockers
17
Q
- anesthetic
- raises ventricular stimulation threshold during diastole = no effect on HR & atrial dysrythmias
A
lidocaine
18
Q
- DOC for rapid anticoagulation
- DOG for pregnancy & lactation
A
heparin
19
Q
- dilates coronary arteris to relieve chest pain
- decrease BP, preload, afterload, & myocardial O2 demands
A
nitroglycerin
20
Q
- naturally occuring nuceloside = activates potassium channels in SA & AV nodes causing potassium to leave cardiac muscle cells
- literaly flatine them for a couple seconds and help them start all over
- PSVT
- CAD
A
adenosine
21
Q
- often used for dentist
- excessive hemorrhage due to clots being dissolved rapidly or prematurely
A
aminocaproic acid
22
Q
- Drug of choice for depression (used for pediatrics & geriatrics)
- Block serotonin
A
SSRI
23
Q
- promote formation of clots
- opposite of anticoagulatns = shorten bleeding times
- prevent fibrin from dissolving
- enhance stability of clot
- prevent excess bleeding
A
hemostatic antifibrinolytic
24
Q
- like dobutamine, but musch longer half-life
- block enzyme in cardiac & smooth muscle = increase amt. available calcium
- *- positive inotropic effect = increase CO
- *- vasodilation
- increase contractility & decrease L ventricular afterload
A
phosphodiesterase III inhibitor
25
- nonselective = Beta 1 & Beta 2
propranolol
26
- borad spectrum
- atrial & ventricular dysrhythmias
- med of choice for atrial dysrhthmias in pt c HF
- resistant v. tach & v. fib that is life-threatening
amniodarone
27
- identical to tPA
- DOC for thrombotic stroke
- also used for severe DVT
- off-labe: restore IV catheter patency
- convert plasminogen to plasmin which dissolves firbin clots
alteplase
28
- large amounts of unbound drug can circulate in plasma = often administered concurrently with ASA or heparin
- highly specific binding c glycoprotein IIa/IIIb receptor
eptifibatide
29
- prevent reabsorption of Na+ in loop of henle
| - 4+ edema, pulmonary edema
furosemide
30
- 1st Gen
- Depresses the cerebral cortex, hypothalamus, & limbic system
- Dopamin antagonist
- Nonphenothiazine
- Acute & chronic psychotic disorders
haloperidol
31
- nodal cells
- decrease automaticity in SA node = slow impulse conduction through AV node = slow HR
* **- prolonged PR interval will be noted on ECG
- control ventricular rate of atrial flutter or a. fib
- relief of chest pain
calcium channel blockers
32
- lengthen clotting time & prevent thrombi forming or growing (DOES NOT DISSOLVE EXISTING CLOTS)
anticoagulants
33
- preferred drug for CPR
- rapid reversal of anaphylaxis
- constricts arterioles, increases BP, dilates airways
epinephrine
34
- break up clots
| - only used for life-threatening
thrombolytics
35
- not active in beta2 receptors
- immediately raise BP
- increase CO output
norepinephrine
36
- Analgesic choice for mngmt of most types of acute & severe chronic pain
- Drug choice for acute chest pain associate with MI
- Mimics action of endogenous endorphins
morphine sulfate
37
- sever HTN
- L&D for preeclampsia
- relaxas arterial smooth muscle = directly @ vessels
- reduces afterload
hydralazine
38
- platelet function reduced as much a 90% within 2 hrs
- acute coronary syndrome
- percutanesous coronary intervention
abciximab
39
reverse resp. depression caused by opioids
nalaxone
40
- more expensive than heparin
- more predictable response = less frequent monitoring
- Factor Xa (10a)
enoxaparin
41
- block sodium channels in myocardial cells = reduce automaticity & slow velocity of action potential
- atrial & ventricular dysrhythmias
procainamide
42
- long duration of action, less significant cardiac effects, & may cause refluc bradycardia
- relief of sinus congestion
- parenteral administration: can prevent or reverse acute hypotension caused by anesthesia or vascular shock
- increase BP
phenylephrine
43
are potassium channel blockers nodal or non-nodal
non-nodal
44
Block reuptake transport of norepinephrine & serotonin
tricyclics
45
- sodium channel inhibitors & aldostern antagonists = counteracts large aldosterone secretion
- polycystic ovarian
- mild HTN in pt's at risk of hypokalemia
sprionalactone
46
- short-term for acute decompensated HF (fluid overload = high BP)
milrinon
47
- Dopamine antagonist
- Positive & negative symptoms of - schizophrenia
- Short-term of acute mania c bipolar
- Depression associated c bipolar
quetiapine
48
- 2nd gen
- Dopamine antagonist
- Neg. Schizophrenia
- Acute mania c bipolar
- Pediatric autism pt’s: irritability
risperidone
49
- block beta-adrenergic receptors
- have effect on Calcium channels
- slow HR & decrease contractility
* **- atrial dysrrhythmias associated with HF
* **- mask hypoglycemia
- work more in nodal in ATRIA
- post-MI = decrease likelihood of sudden death
Beta Blockers
50
- Major depression
- Seasonal affective disorder
- Management of nicotine withdrawal
- Off label: Neuropathic pain & ADHD
bupropion
51
Not the best choice unless others are not working = 2nd line agent when other opioids are contraindicated
meperidine
