Final - MOA Flashcards
(56 cards)
1
Q
- hypernatremia
- cellular dehydration
- dehydrated + normal BP
A
hypotonic
2
Q
stimulate uterine contractions & promote induction of labor
A
oxytocics
3
Q
- cross BBB
- preferred drug for initial HIV treatment
A
efavirenz
4
Q
antivirals:
- prodrug = more commonly prescribed
A
valacyclovir
5
Q
- volume expander
- massive hemorrhage
- shock
- burns
- acute liver failure
A
colloids
6
Q
- aerobic gram-neg = narrow spectrum
- effective against gram-neg: bacterial protein synthesis inhibitor
A
aminoglycosides
7
Q
antivirals:
- flu A or B
- N = neurominoade
A
oseltamivir
8
Q
- prophylaxis of bacterial infection
- gram-pos
A
vancomycin
9
Q
- generally broad-spectrum
- 4 generations (1st gram-neg, 5th gram-pos)
- DNA synthesis inhibitors
A
flouroquinolones
10
Q
sometimes mom gets too much oxytocin and there is no relaxation & too much activity = too long of contraction = can administer _____
A
terbutaline
11
Q
- arthritis, inflammatory conditions, pediatric patent ductus arteriosus
A
indomethacin
12
Q
- control postpartum hemorrhage & restore uterine tone
A
methylergonovine
13
Q
is amphotericin broad or narrow spectrum
A
borad
14
Q
- affects DNA so it can’t replicate
- gram-neg
- broad-spectrum
- medication for anthrax
A
ciprofloxacin
15
Q
- 5th Gen
- extreme cases of MRSA
A
ceftrialone
16
Q
- PI = most common for protease inhibitor category
A
lopinavir with ritonavir
17
Q
antivirals:
- prophylactic (cancer exposed, pregnancy, children 3-4, adults)
- parkinson’s (ween off)
A
amantadine
18
Q
- controlling postpartum hemorrhage
- inducing abortion 13-20 wks
A
carbaprost
19
Q
- acts by inhibiting the synthesis of mycolic acid
- main prototype drug for latent TB
- bacteriocidal = active
- bacteriostatic = dormant
A
isoniazide
20
Q
- usually for gastric ulcers
- first line after oxytocin
A
misoprostol
21
Q
- inhibit cell wall
- 4 generations (1st gramp-pos, 5th gram-neg)
- bacteriocidal and inhibit cell wall synthesis by binding PBPs
- used to treat step throat in pt. who has nka
A
cephalosporins
22
Q
- creates a defective proviral DNA strand
- dirty needle stick
- pregnancy moms to reduce transmission to fetus
A
zidovoudine
23
Q
- reduce postpartum hemorrhage
- incomplete or inevitable abortion
A
oxytocin
24
Q
- supress uterine contractions
- delay birth 24-72 hrs (long enough to improve fetal lung)
A
tocolytics
25
- 1st Gen.
- give prior to surgery
- strept thoat
cefazolin
26
tocolytic: usualy fot HTN & angina
nifedipin
27
tocolytic for preeclampsia
magnesium sulfate = reduce risk of seizure
28
colloids have a _____ effect
hypertonic
29
- usually for asthma
| - suppress preterm contractions
terbutaline
30
- choice tocolytic for preterm labor
magnesium sulfate
31
cellular edema (cerebral edema)
hypertonic
32
- affects gram-post, gram-neg, aerobic, anaerobic = broad spectum
- resistant to beta lactamase and are broad-spectrum alternatives to PCNs
carbapenems
33
- 3rd gen (more broad than cipro)
| - long half-life = once daily dosing
levofloxacin
34
- first line drug for active TB
- always given in combination with other meds
- meningitis, leprosy, cross BBB
- affects RNs synthesis in microbacteria
rifampin
35
- herpers
| - N, V
acyclovir
36
- anaerobic bacterial infections (respiratory, bone, skin, CNS), amebiasis
- C. Diff
metronidazole
37
- 3rd Gen
| - one time IM injection
ceftriaxone
38
Antineoplastic:
- non-specific drug
- liver converts it to active form
cyclophosphamide
39
Antineoplastic:
| - cell cycle non-specific = broad spectrum
doxorubicin
40
Antineoplastic:
- periwinkle plant
- works only in M phase of cell cycle = inhibits division
vincristine
41
Antineoplastic:
- hormones, female related
- stimulate ovulation in women c infertility
tamoxifen
42
Antineoplastic:
- cell-specific
- severe RA
- psoriases
- autoimmune disorders
- abortion
methrotrexate
43
Biological Response Modifier:
- trying to make us get some RBC's = bring up hct
- anemia
- kidney failure
epoetin alfa
44
Biological Response Modifier:
- G-CSF factor
- low ANC (<5-10k)
fligrastin
45
Biological Response Modifier:
| - give when you have low platelets
romiplostim
46
- calcineurin inhibitor
- low activity of T-cell in immune system
- RA
- organ transplant rejection
- off label: autoimmune disease
cyclosporine
47
- short acting
- usually combined with longer-lasting
- emergency DKA
- hyperosmolar hyperglycemic state (HHS)
- increases cellular uptake of glucose = decrease BG
- stimulates storage of glucose as glycogen
- inhibits release of glucagon
regular insulin
48
- intermediate acting
- CLOUDY = draw up after another insulin
- provide basal level of insulin coverage for between meals & night
NPH
49
- rapid acting
| - usually given with long acting
aspart & lispro
50
- long acting insulin
glargine
51
- synthetic analog of human ADH that has longer duration of action than natural hormone
- polyuria, polydipsia
- off-labe: enuresis
- produces increase in plasma factor VIII and von Willibrand's
desmopressin
52
- mimic those of endogenous corticosteroids
- inflammation & allergies
- RSV = open airway
hydrocortisone
53
antihypoglycemic:
- very thick substance
- NO PUSH!
- hypertonic
D50W
54
- increase BS
| - emergency hypoglycemia
glucagon
55
- hyperthyroidism
| - inhibits synthesis of thyroid hormones
methimazole
56
- prior to thyroid surgery = reduce vascularity, fragility, & size of thyroid glands
- hyperthyroidism
- protect thyroid from radiation
Potassium iodide
