Final 2 - Oral Manifestations of AIDS Flashcards Preview

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Flashcards in Final 2 - Oral Manifestations of AIDS Deck (19)
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1

Estimated # of people living with HIV

30,000,000

2

People in US diagnosed with HIV each year

50,000

3

Percentage of HIV patients with oral manifestations

40%

4

Percentage of HIV patients with oral cavity pain

28%

5

Fungal Infections (Type, Test, Treat)

Type: Candidiasis (pseudomembranous, atrophic, hyperplastic, angular chelitis)

Test: exfoliative cytology with KOH

Treat:
Topical (nystatin, clotrimazole, vytone cream, mycolog cream)
Systemic (fluconazole)

6

Deep Fungal Infections (Presentation, Treat)

Histoplasmosis
5% of AIDS pts

Painful, indurated ulcers on palate, gingiva, tongue

Treat: Anti-fungals

7

HSV Implications and Treatment

CD4 count 4wks can indicate progression to AIDS

Treat:
CD4 >200 Acyclovir
CD4 <200 Systemic antiviral

8

Varicella-Zoster Appearance and Treatment

Shingles - single dermatome, painful vesicles

Treat: systemic anti-virals

9

Epstiein Barr Virus Associations

General population:
Nasopharyngeal carcinoma
Burkitt's Lymphoma

AIDS:
Hairy leukoplakia
Non-Hodgkin Lymphoma

10

Oral Hairy Leukoplakia Appearance

25% of AIDS pts
CD4 <300

White, vertical fissures on ventral/lateral tongue

No tx

11

Cytomegalovirus (Present, Test, Treat)

Painful, persistant ulcers on palate and gingiva
May cause blindness in HIV

Test: deep biopsy, owl eyes

Treat: Systemic antiviral

12

HPV (Present, Treat)

Wart on lip, gingiva, palate
Soft, pink, cauliflower
Some strains cause dysplasia -> SCC

Treat: excision

13

Linear Gingival Erythema (Present, Treat)

Red band on gingiva
Petechiae, spontaneous bleeding

Treat: Oral hygiene

14

NUG (Present, Treat)

Necrotizing Ulcerative Gingivitis

Necrosis of inter-dental papillae
Pain, gingival bleeding, swelling
Alveolar bone loss

Treat: Debride, Antibiotics

15

Kaposi Sarcoma

Most common tumor in AIDS
Associated with HHV-8
Decreased with HAART

16

Non-Hodgkin Lymphoma (Epi, Treat)

Second most common tumor in AIDS
Has not decreased with HAART
5% of pts
Median survival: <1yr

Treat: chemo, radiation

17

Oral SCC

Usually HPV 16
Presents 10yrs earlier in HIV pts than general pop

18

Major Aphthous Treatment

Dexamethasone
Clobetasol

19

Lymphoepithelial Cyst Presentation

Painless, bilateral parotid enlargement