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1

(probably) the most communicable disease

measles

2

measles is caused by what virus?

paramyxovirus

3

measles (enveloped/nonenveloped), (negative/positive) sensed, (single/double) stranded (RNA/DNA) virus

enveloped, negative sense, single stranded RNA (-ssRNA)

4

What causes the characteristic measles rash?

Tc cells targeting measles-infected endothelial cells of the capillaries

5

What is measles known for?

Propensity to cause cell fusion, leading to the formation of giant cells, and allowing the viruses to pass directly from cell to ell and escape Ab-neutralization

6

What population is most at risk for mortality from measles?

children in poor, developing countries

7

Why do people die of bacterial pneumonia when they have measles?

measles causes a temporary immunosuppression

8

does measles have an iceberg effect?

no

9

does mumps have an iceberg effect?

yes

10

Rubella is (enveloped/nonenveloped), (negative/positive) sensed, (single/double) stranded (RNA/DNA) virus

enveloped, +ssRNA

11

Rubella is caused by

togovirus

12

Measles, mumps, and rubella are all spread by

respiratory droplets

13

MMR vaccine is (live/dead)

live, attenuated

14

Of the three, which virus is closest to eradication

measles

15

A disease that normally exists in other animals, but can be transmitted and infect humans

zoonosis

16

transfers microbe; animals, insects and inanimate (fomite)

vector

17

What class of viruses are most likely to mutate?

ssRNA

18

Why are ssRNA viruses most likely to mutate?

RNA polymerase error prone (no 'spell check') and no second strand for proof reading

19

hosts in which the infectious agents do not normally develop but when occasionally, chance infections do occur, the agent is able to complete its lifecycle

accidental hosts

20

hosts in which the infectious agents do not normally develop, but when occasionally, chance infections do occur, the agent is unable to complete its lifecycle, produce many infectious particles, or be passed onto another person

dead end hosts

21

What 2 genera of enveloped ssRNA viruses contain a growing number of insect and rodent borne pathogens

arboviruses and roboviruses

22

3 types of arboviruses

tobaviruses, flaviviruses, bunyaviruses

23

of the 3 arboviruses, which are +, which are neg?

togaviruses, flaviviruses are +, bunyaviruses are -

24

Roboviruses have which vector?

rodent borne

25

one genera of roboviruses

arenavirus

26

Arenaviruses are + or -

-ssRNA

27

arenaviruses are enveloped, non enveloped

enveloped

28

What causes transmissible spongiform encephalopathies?

prions

29

rare, slow, degenerative diseases of the brain that result in a 'spongy' looking brain (multiple holes where neurons should be)

transmissible spongiform encephalopathies

30

have no virus structure or genome, elicit no immune response, and are extremely resistant to inactivation by heat, disinfectants, and radiation

prions