Flashcards in Midterm Deck (59)
protein shell that may be icosahedral or helical in shape
Enclosed within the capsid
genetic material: either DNA or RNA, single or double stranded
What are 5 cellular outcomes of viral infections?
abortive, lytic, chronic (non-lytic), latent, transformation
Which of the 5 cellular outcomes of viral infections is defined as no progeny viruses are produced?
Which of the 5 cellular outcomes of viral infections is defined as usually an acute process where viral progeny are released by death of the cell
Which of the 5 cellular outcomes of viral infections is defined as infected cells slowly release viral progeny, without cell death
Which of the 5 cellular outcomes of viral infections is defined as virus genome usually become integrated into the cell DNA, where it becomes dormant for various times. The viruses may "reawaken" at anytime and begin to produce progeny, and then become quiescent again.
Which of the 5 cellular outcomes of viral infections is defined as the virus causes the cell to proliferate in an uncontrolled manner
message that says, “make 1000 copies of this message and 1000 capsids and place the message into the capsid”
protein bottle that contains the genome
What are the 4 major types of viral genomes that viruses might have
dsDNA, ssDNA, dsRNA, ssRNA
Which type of viral genome has the highest mutation rate
ssRNA- doesn't have the repair enzyme of DNA or the second strand to double check
What are 4 basic morphologies of viruses?
Naked icosahedral, naked helical, enveloped helical, enveloped icosahedral
What must viruses produce in order to replicate their protein components?
positive stranded mRNA
What are 4 functions of sIgA?
sticks to mucins, resistant to proteases, neutralizes viruses/toxins, block colonization of microbes
What is cleaved to form the secretory portion of sIgA
... cells process and present Ag on class ... ... molecules
M-cells; II HLA
(salk/sabin) non infectious
(salk/sabin) induces great sIgA protection (and good IgG)
(salk/sabin) induces great IgG protection
What class of virus is polio?
How is polio spread
What class of virus is influenza?
What must influenza have?
functional RNA-dependent, RNA polymerase
How is the influenza genome unique?
Segmented, found in 8 different pieces associated with 8 separate nucleocapsids within each viral particle.