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Flashcards in Midterm Deck (59)
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1

protein shell that may be icosahedral or helical in shape

capsid

2

Enclosed within the capsid

genetic material: either DNA or RNA, single or double stranded

3

What are 5 cellular outcomes of viral infections?

abortive, lytic, chronic (non-lytic), latent, transformation

4

Which of the 5 cellular outcomes of viral infections is defined as no progeny viruses are produced?

Abortive

5

Which of the 5 cellular outcomes of viral infections is defined as usually an acute process where viral progeny are released by death of the cell

lytic

6

Which of the 5 cellular outcomes of viral infections is defined as infected cells slowly release viral progeny, without cell death

chronic, non-lytic

7

Which of the 5 cellular outcomes of viral infections is defined as virus genome usually become integrated into the cell DNA, where it becomes dormant for various times. The viruses may "reawaken" at anytime and begin to produce progeny, and then become quiescent again.

Latent

8

Which of the 5 cellular outcomes of viral infections is defined as the virus causes the cell to proliferate in an uncontrolled manner

transformation

9

message that says, “make 1000 copies of this message and 1000 capsids and place the message into the capsid”

genome

10

protein bottle that contains the genome

capsid

11

What are the 4 major types of viral genomes that viruses might have

dsDNA, ssDNA, dsRNA, ssRNA

12

Which type of viral genome has the highest mutation rate

ssRNA- doesn't have the repair enzyme of DNA or the second strand to double check

13

What are 4 basic morphologies of viruses?

Naked icosahedral, naked helical, enveloped helical, enveloped icosahedral

14

What must viruses produce in order to replicate their protein components?

positive stranded mRNA

15

What are 4 functions of sIgA?

sticks to mucins, resistant to proteases, neutralizes viruses/toxins, block colonization of microbes

16

What is cleaved to form the secretory portion of sIgA

Fc receptor

17

... cells process and present Ag on class ... ... molecules

M-cells; II HLA

18

(salk/sabin) non infectious

salk

19

(salk/sabin) infectious

sabin

20

(salk/sabin) induces great sIgA protection (and good IgG)

sabin

21

(salk/sabin) induces great IgG protection

salk

22

(salk/sabin) injected

salk

23

(salk/sabin) ingested

sabin

24

What class of virus is polio?

(+)ssRNA

25

polio (enveloped/nonenveloped)

nonenveloped

26

How is polio spread

fecal-oral

27

What class of virus is influenza?

(-)ssRNA

28

What must influenza have?

functional RNA-dependent, RNA polymerase

29

How is the influenza genome unique?

Segmented, found in 8 different pieces associated with 8 separate nucleocapsids within each viral particle.

30

What are the 2 spike proteins on influenza?

Neuraminidase (N protein), hemagglutinin (H protein)