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Flashcards in Final Deck (165)
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1

What are the indications of ECT?

Severe or treatment resistant MDD or bipolar disorder

2

What is the efficacy (%) for ECT?

80%

3

What is the procedure for ECT?

Electrical current passes thru the brain, causing a seizure

4

What is used prior to ECT treatment?

General anesthesia and a muscle relaxant

5

What are the SE of ECT?

Confusion
Possible memory deficits

6

What are the relative contraindications for ECT?

H/p treatment resistance, need for rapid treatment response, and severity of illness

7

What are the NTI medications?

Li
CBZ

8

Which medications increase suicidality?

Mood stabilizers except Li

9

What is the MOA of Li?

Alter cation transport
Neurotransmitter reuptake
Effects of send messenger systems

10

Which drugs have an MOA of VSSCa?

VPA
CBZ
OxCBZ
Lamictal

11

What is topiramates MOA?

Interferes with both Ca and Ca channels

12

What is pregabalin/gabapentin's MOA?

Alpha-2-delta ligands

13

What is keppra's MOA?

Inhibition of N-type Ca channels

14

What are the WD sx of benzos?

Anxiety
Agitation
Insomnia
Restlessness
Muscle tension
Irritability

15

What are the WD sx of TCAs?

Cholinergic rebound

16

What are the WD sx of SSRIs?

Fatigue, lethargy, flu-like sx, dizziness, n/d, HA

17

What are the WD sx of paxil?

Cholinergic rebound

18

What are the WD sx of duloxetine?

Severe WD reported

19

What are FGA MOAs?

Block D2 receptors

20

What are SGA MOA?

Blocks D2 receptors
Selective modifying effects of 5HT2A antagonism

21

What is the first line treatment of MDD?

SSRI
SNRI
Mirtazapine
Bupropion

22

What is the first line treatment of bipolar mania?

Li
BPA
SGAs
Consider 2 drug combo if severe

23

What is the first line treatment of bipolar depression?

Li
Lamictal
Quetiapine
VPA

24

What is the first line treatment of mixed bipolar depression?

CBZ
VPA
Olanz

25

What is the first line treatment of GAD?

SSRI
SNRI

26

What is the first line treatment of panic disorder?

SSRI
SNRI
CBT

27

What is the first line treatment of OCD?

CBT AND SSRIs

28

What is the first line treatment of PTSD?

SSRI (relieves core PTSD sx)

29

What is the first line treatment of psych emergencies?

APX for acute agitation
Haldol used most often
SGAs

30

What is the first line treatment of schizophrenia?

SGA
DA