final lecture 8 Flashcards
1
Q
PT reflects
A
extrinsic pathway
2
Q
aPTT reflects
A
intrinsic pathway
3
Q
INR reflects
A
factors II, VII, X
4
Q
heparin treatment dosing
A
initiation: 8units/kg bolus
followed by infusion: 18 units/kg/h
5
Q
heparin monitoring
A
aPTT 1.5-2.5
6
Q
major bleeding w/ heparin
A
when 2g decrease in Hgb
7
Q
heparin antidote
A
1 mg protamine sulfate will neutralize 100 units of heparin
8
Q
enoxaparin therapeutic dose
A
1mg/kg Q12H
9
Q
dalteparin therapeutic dose
A
200 units/kg Q24H
10
Q
LMWH monitoring
A
CBC
11
Q
fondaparinux doses
A
100kg: 10mg QD
12
Q
at what time of day should you give warfarin?
A
at bedtime
13
Q
warfarin dose
A
5-10mg if 65
14
Q
need UFH or LMWH to ____
A
bridge until patient reaches therapeutic range w/ warfarin
15
Q
time to steady state on warfarin
A
8-15 days