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Flashcards in final lecture 9 Deck (17):
1

HAT

plt sequestration

2

HIT

IgG antibodies

3

diagnosis of HIT

4T score
thrombocytopenia
timing
thrombosis
other

4

agratroban dose

DTI
alt. anticoag in HIT
2mcg/kg/min
goal aPPTL 1.5-3

5

lepirudin

DTI
alt. anticoag in HIT
aPTT 4 hours after initiation: 1.5-2

6

bivalirudin

DTI
alt. anticoag in HIT

7

drug induced thrombocytopenia

quinine, quinidine, vancomycin, heparin, pip/tazo

8

drug-induced aplastic anemia

2 of theses:
WBC<30,000

9

severe aplastic anemia

2 of these:
ANC<20,000
anemia

10

drug induced aplastic anemia causes

chloramphenicol, felbamate, antineoplastic agents

11

drug induced agranulocytosis causes

beta-lactam ABX, valprioc acid, clozapine

12

agranulocytosis management

GF support for chemo induced

13

drug induced hemolytic anemia diagnosis

coombs test

14

hemolytic anemia drug causes

beta-lactam ABX, methyldopa

15

drug induced oxidative hemolytic anemia most common cause

G6PD deficiency
drugs- dapsone, sulamethoxazole

16

drug induced megaloblastic anemia causes

metformin, methotrexate, phenytoin & phenobarbital

17

megaloblastic anemia treatment

folate & vit B12