Flashcards in Final Review Deck (93)
Lipids are ______ compounds that are soluble in organic solvents
most membrane lipids are _____, having non polar end and a polar end
_______ consist of a hydrocarbon chain w/ a carboxylic acid at one end
double bonds in fatty acids usually have a ____ configuration
in the family of glycerol, we have fatty acids and triglycerides. which is the largest in the family?
what is the glycerol specific for second messages
phospholipids have 2 big players in the second messenger pathway, what are they
phosphatidyl inositol (PI) pathway and the fact that arachidonic is stored in phospholipids and can be cleaved off this to start the inflammatory processes.
what position is arachidonic acid found in
the ______ due to the double bond gives cis conformation its bend and changes the ____ of lipids
______ are important for neurons. they myelinate axons
sphingomyelin is important for the _____
-it is not important for the retina bc there are no myelinated nerves there
what is the fluidity of a phospholipid determined by?
the fatty acid composition as well as other molecules such as cholestoerl.
how can you increase the fluidity?
1. increase areas of unsaturated fatty acids
2. increase cholesterol
what kind of ring does cholestoerol have? what kind of branched hydrocarbon tail does it have?
short branched hydrocarbon tail
cholesterol is hydrophobic or hydrophillic?
that bitch is largely hydrophobic
cholesterol has one polar group called _____. making it amphipathic
how do we get cholesterol?
we can make it if we dont get it in our diet
cholesterol maintains the unique characteristics of ________ and also steroidal building block for the ______ family
there is LDL and HDL. which is good and bad
LDL is bad
HDL is good
how do lipids end up getting to the cells w/in the eye, expecially the outer and inner segments?
they have to be transported through the RPE via a lipid carrier (HDL or LDL-like)
what is the first lipid layer in the eye
the tear film
which cholesterol gets the lipids into the eye?
we have a ____ like system that moves lipids through the eye
where does vitamin A in your diet come frmo?
how do eskimos get their vitamin A from? lol wtf
a person who consumes plant material gets their vitamin A through ....
how does cholesterol get into your eye
it gets metabolized in the intestine, attaches to the chylomicron pathway, go through the lympathic system, goes to the liver, packages it w/ serum retinol binding protein.
can lipids move through the cellular system w/o a carrier function?
uhh fk no
what is formed in Stargardt
where does it come from? what is defective?
it comes from retinol (retinaldehyde).
the flipase is defective