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Flashcards in Final Review Deck (93)
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1

Lipids are ______ compounds that are soluble in organic solvents

non-polar (hydrophobic)

2

most membrane lipids are _____, having non polar end and a polar end

amphipathic

3

_______ consist of a hydrocarbon chain w/ a carboxylic acid at one end

fatty acids

4

double bonds in fatty acids usually have a ____ configuration

cis

5

in the family of glycerol, we have fatty acids and triglycerides. which is the largest in the family?

glycerophospholipd

6

what is the glycerol specific for second messages

phosphatidyl inositol

7

phospholipids have 2 big players in the second messenger pathway, what are they

phosphatidyl inositol (PI) pathway and the fact that arachidonic is stored in phospholipids and can be cleaved off this to start the inflammatory processes.

8

what position is arachidonic acid found in

SN2 position

9

the ______ due to the double bond gives cis conformation its bend and changes the ____ of lipids

kink
fluidity

10

______ are important for neurons. they myelinate axons

sphingolipids

11

sphingomyelin is important for the _____
-it is not important for the retina bc there are no myelinated nerves there

lens

12

what is the fluidity of a phospholipid determined by?

the fatty acid composition as well as other molecules such as cholestoerl.

13

how can you increase the fluidity?

1. increase areas of unsaturated fatty acids
or
2. increase cholesterol

14

what kind of ring does cholestoerol have? what kind of branched hydrocarbon tail does it have?

rigid ring
short branched hydrocarbon tail

15

cholesterol is hydrophobic or hydrophillic?

that bitch is largely hydrophobic

16

cholesterol has one polar group called _____. making it amphipathic

hydroxyl

17

how do we get cholesterol?

we can make it if we dont get it in our diet

18

cholesterol maintains the unique characteristics of ________ and also steroidal building block for the ______ family

plasma membrane
corticosteroid family

19

there is LDL and HDL. which is good and bad

LDL is bad
HDL is good

20

how do lipids end up getting to the cells w/in the eye, expecially the outer and inner segments?

they have to be transported through the RPE via a lipid carrier (HDL or LDL-like)

21

what is the first lipid layer in the eye

the tear film

22

which cholesterol gets the lipids into the eye?

LDL

23

we have a ____ like system that moves lipids through the eye

HDL

24

where does vitamin A in your diet come frmo?

veggies

25

how do eskimos get their vitamin A from? lol wtf

liver

26

a person who consumes plant material gets their vitamin A through ....

beta carotene

27

how does cholesterol get into your eye

it gets metabolized in the intestine, attaches to the chylomicron pathway, go through the lympathic system, goes to the liver, packages it w/ serum retinol binding protein.

28

can lipids move through the cellular system w/o a carrier function?

uhh fk no

29

what is formed in Stargardt
where does it come from? what is defective?

A2E
it comes from retinol (retinaldehyde).
the flipase is defective

30

are flip-flop of lipids fast or slow?

slow