Flashcards in Fiser Absite. Ch 01-02. Cell Biology. Hematology Deck (130)
What molecule increases membrane fluidity?
What is responsible creating the charge of cells? What is does it move and what is the net charge (positive or negative)?
Na/K ATPase, 3 Na+ out and 2 K+ in, negative
What are the adhesion molecules that form cell-cell and cell-extracellular matrix adhesions?
What forms cell-cell occluding junctions to form an impermeable barrier (ie epithelium)?
What type of junctions allow communication between cells and what are their subunits called?
gap junctions, connexin
What is the intramembrane protein that transduces a signal from receptor to response enzyme?
What are the phases of the cell cycle?
G1, S, G2, M
Which phase of the cell cycle is the most variable and determines the cycle length?
What is quiescent cell cycle phase called?
What are the 4 phases of mitosis?
Prophase, Metaphase, Anaphase, Telophase
centromere attachment, spindle formation, nucleus disappears
In which phase of mitosis does chromosome alignment occur?
In which phase of mitosis are the chromosomes pulled apart?
In which phase of mitosis does a separate nucleus form around each set of chromosomes?
The outer membrane of the nucleus is continuous with what other structure?
rough endoplasmic reticulum
Where are ribosomes made?
Steroid hormone - binds receptor in _____ then enters nucleus and acts as transcription factor.
Thyroid hormone - binds receptor in ____, then acts as transcription factor.
What are the purines?
What are the pyrimidines?
cytosine, thymidine, (uracil in RNA)
In glycolysis, 1 glucose molecule generates how many ATP and pyruvate molecules
Where does the Krebs cycle occur?
What is the overall ATPs produced from 1 molecule of glucose?
What is converted to glucose in gluconeogenesis?
lactic acid and amino acids
An elegant mechanism for the hepatic conversion of muscle lactate into new glucose. Pyruvate plays a key role in this process.
What organelle synthesizes proteins that are exported (increased in pancreatic acinar cells)?
Rough endoplasmic reticulum
In what organelle does lipid/steroid synthesis as well as drug detox (increased in liver and adrenal cortex)?
Smooth endoplasmic reticulum
What organelle modifies proteins with carbohydrates; proteins are then transported to the cell membrane, are secreted or are targeted to lysosomes?
Activated by calcium and diacylglycerol (DAG). Phosphorylates other enzymes and proteins.
Protein kinase C