Fiser Absite. Ch 01-02. Cell Biology. Hematology Flashcards Preview

Fiser Absite > Fiser Absite. Ch 01-02. Cell Biology. Hematology > Flashcards

Flashcards in Fiser Absite. Ch 01-02. Cell Biology. Hematology Deck (130)
Loading flashcards...
1

What molecule increases membrane fluidity?

Cholesterol

2

What is responsible creating the charge of cells? What is does it move and what is the net charge (positive or negative)?

Na/K ATPase, 3 Na+ out and 2 K+ in, negative

3

What are the adhesion molecules that form cell-cell and cell-extracellular matrix adhesions?

desmosomes/hemidesmosomes

4

What forms cell-cell occluding junctions to form an impermeable barrier (ie epithelium)?

tight junctions

5

What type of junctions allow communication between cells and what are their subunits called?

gap junctions, connexin

6

What is the intramembrane protein that transduces a signal from receptor to response enzyme?

G proteins

7

What are the phases of the cell cycle?

G1, S, G2, M

8

Which phase of the cell cycle is the most variable and determines the cycle length?

G1

9

What is quiescent cell cycle phase called?

G0

10

What are the 4 phases of mitosis?

Prophase, Metaphase, Anaphase, Telophase

11

centromere attachment, spindle formation, nucleus disappears

Prophase

12

In which phase of mitosis does chromosome alignment occur?

Metaphase

13

In which phase of mitosis are the chromosomes pulled apart?

Anaphase

14

In which phase of mitosis does a separate nucleus form around each set of chromosomes?

Telophase

15

The outer membrane of the nucleus is continuous with what other structure?

rough endoplasmic reticulum

16

Where are ribosomes made?

Nucleolus

17

Steroid hormone - binds receptor in _____ then enters nucleus and acts as transcription factor.

nucleus

18

Thyroid hormone - binds receptor in ____, then acts as transcription factor.

cytoplasm

19

What are the purines?

adenine, guanine

20

What are the pyrimidines?

cytosine, thymidine, (uracil in RNA)

21

In glycolysis, 1 glucose molecule generates how many ATP and pyruvate molecules

2 each

22

Where does the Krebs cycle occur?

mitochondrial matrix

23

What is the overall ATPs produced from 1 molecule of glucose?

36

24

What is converted to glucose in gluconeogenesis?

lactic acid and amino acids

25

An elegant mechanism for the hepatic conversion of muscle lactate into new glucose. Pyruvate plays a key role in this process.

Cori Cycle

26

What organelle synthesizes proteins that are exported (increased in pancreatic acinar cells)?

Rough endoplasmic reticulum

27

In what organelle does lipid/steroid synthesis as well as drug detox (increased in liver and adrenal cortex)?

Smooth endoplasmic reticulum

28

What organelle modifies proteins with carbohydrates; proteins are then transported to the cell membrane, are secreted or are targeted to lysosomes?

Golgi apparatus

29

Activated by calcium and diacylglycerol (DAG). Phosphorylates other enzymes and proteins.

Protein kinase C

30

Activated by cAMP. Phosphorylates other enzymes and proteins.

Protein kinase A