flashcards from articles

(39 cards)

1
Q

What is the neuromatrix theory of pain?

A

A theory that pain is generated by a ‘neurosignature’ within a brain network (body-self neuromatrix), not just from injury.

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2
Q

What is a neurosignature?

A

A pattern of neural activity that produces the pain experience, influenced but not caused by sensory input.

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3
Q

What are the main brain structures involved in the neuromatrix?

A

Thalamus, cortex, and limbic system.

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4
Q

How does the neuromatrix explain phantom limb pain?

A

It shows that pain can be felt without any physical input, as it is generated by the brain.

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5
Q

What role does stress play in chronic pain according to Melzack?

A

Stress activates hormonal responses (e.g., cortisol) that can damage tissues and contribute to pain.

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6
Q

What are the four key conclusions from the neuromatrix model?

A

1) Body is felt due to brain processes; 2) Pain can exist without input; 3) The self is unified; 4) Brain patterns are genetically programmed.

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7
Q

What are the three stages of tendinopathy in the continuum model?

A

Reactive tendinopathy, tendon dysrepair, and degenerative tendinopathy.

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8
Q

What happens in reactive tendinopathy?

A

Swelling due to acute overload, with increased proteoglycans and water—reversible with load management.

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9
Q

What defines the degenerative stage of tendinopathy?

A

Irreversible changes like matrix disorganization and cell death, often without pain.

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10
Q

Why might tendon structure and pain not align?

A

Many people show structural changes without pain; pain is influenced by load-related signaling.

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11
Q

What is reactive-on-degenerative tendinopathy?

A

A new reactive flare-up on an existing degenerative tendon.

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12
Q

What does the quote ‘treat the doughnut, not the hole’ mean in tendinopathy?

A

Focus on strengthening the healthy part of the tendon, not the degenerated portion.

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13
Q

What is the key idea of Bialosky’s updated MT model?

A

MT relieves pain through neurophysiological responses, not just mechanical correction.

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14
Q

What are the three zones in the MT mechanism model?

A

Zone 1: Provider-patient interaction; Zone 2: Nervous system response; Zone 3: Clinical outcomes.

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15
Q

How can MT alter pain processing in the nervous system?

A

Via peripheral, spinal, and supraspinal effects, including fMRI evidence of reduced brain activation in pain regions.

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16
Q

What are two psychophysical tools used to assess pain modulation?

A

Conditioned Pain Modulation (CPM) and Temporal Summation.

17
Q

What makes MT effects patient-specific?

A

Patient beliefs, expectations, and provider interaction all influence outcomes.

18
Q

Why might people resist identifying as ‘patients’?

A

It can feel disempowering and reduce their perceived value in care settings.

19
Q

What is the significance of the ‘8760 hours’?

A

Most people manage their condition themselves outside the few hours spent with a provider.

20
Q

How can providers better engage patients?

A

By asking about their life, validating their efforts, acknowledging loss of control, and practicing empathy.

21
Q

What is a key critique of patient-centered care in this article?

A

Systems often focus more on procedures than truly seeing and respecting the person.

22
Q

How should exercise for OA be tailored?

A

To the patient’s needs and preferences.

23
Q

When is aquatic exercise recommended for OA?

A

If land-based exercises are too painful.

24
Q

How long should supervised therapy for OA last initially?

A

At least 6 weeks; some may need 12 weeks.

25
What is the role of 'booster' sessions for OA?
To support long-term OA pain and health management after initial therapy.
26
Why are home exercises important for OA?
They optimize long-term outcomes.
27
What should patients understand about exercise and pain flare-ups?
How to manage and modify exercises during flare-ups.
28
What is Patellofemoral Pain (PFP)?
The most common knee injury in runners. ## Footnote PFP is characterized by pain around the kneecap, often exacerbated by activity.
29
What abnormal kinematics are often observed in runners with PFP?
Notable abnormal kinematics include: * Excessive hip adduction (HADD) * Contralateral pelvic drop (CPD) * Sometimes increased hip internal rotation ## Footnote These kinematic abnormalities can contribute to elevated stress on the patellofemoral joint.
30
What impact do repetitive loading patterns have on runners with PFP?
They can elevate patellofemoral joint stress and exacerbate pain. ## Footnote This stresses the importance of addressing kinematic abnormalities to reduce pain.
31
What was the objective of the study on runners with PFP?
To assess if a simple 10% increase in step rate (cadence) can: * Improve frontal-plane kinematics (hip & pelvis) * Reduce pain and improve function * Produce lasting changes at 4 weeks and 3 months
32
How many runners participated in the study?
12 runners with PFP and aberrant frontal-plane kinematics. ## Footnote The sample size is relatively small, which may affect the generalizability of the results.
33
What method was used for gait retraining in the study?
1 session using a metronome as an audible cue for increased step rate. ## Footnote Runners self-monitored their progress using a GPS smartwatch and metronome app.
34
What kinematic improvements were observed at 4 weeks and 3 months?
Improvements included: * ↓ CPD by 3.1° (4 weeks), 2.7° (3 months) * ↓ HADD by 4.0° (4 weeks), 2.8° (3 months) * ↓ peak knee flexion during stance by ~4° ## Footnote No significant change in hip internal rotation was noted.
35
What clinical improvements were reported at 4 weeks and 3 months?
Clinical improvements included: * ↓ Worst pain from 6.2 to 1.0 (4 weeks) and 0.3 (3 months) * ↑ LEFS by 17.4 points at 3 months (above MCID of 9) * ↑ weekly running volume & pain-free distance significantly
36
What mechanisms were proposed for the observed improvements?
Proposed mechanisms include: * ↑ cadence enhances gluteus medius activation in swing phase → improved hip/pelvis stability * ↓ knee flexion reduces patellofemoral joint force ## Footnote These mechanisms work together to reduce joint stress and pain.
37
What are the clinical implications of the study findings?
Cadence retraining is a simple, low-cost, and clinically effective strategy that: * Can be self-administered using common tools (smartwatch + app) * Reinforces the need to assess biomechanics before implementing gait changes
38
True or False: A 10% increase in running cadence is an ineffective intervention for runners with PFP.
False ## Footnote The study highlights that this intervention leads to significant, sustained improvements in biomechanics and clinical outcomes.
39
Fill in the blank: A 10% increase in running cadence is a practical and effective ______ for runners with PFP.
[intervention] ## Footnote This emphasizes the importance of individualized, kinematics-based interventions in injury rehabilitation.