Fluids and electrolytes Flashcards

(65 cards)

1
Q

Trancellular (water distributions in body)

A

Lymph systems

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2
Q

How is fluid balance regulated

A

CNS, kidneys and heart

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3
Q

RAAS

A

Renal -Angiotensin-
Aldosterone System

when water is too high, ADH in the hypothalamus etc.

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4
Q

Where is fluid lost?

A

Sensible loss:
Kidneys—urine
Intestinal tract—faeces
Skin—perspiration (droplets)

Insensible water loss:
Through the lungs with
exhalation
Evaporation through skin
(perspiration - immediate loss)

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5
Q

Normal range

A

Na 135 – 145 mmol/L
Cl 100 – 106 mmol/L
Ca 2.1 - 206 mmol/L
K 3.5 – 5.0 mmol/L
PO4 2.5 – 4.5 mmol/L
Mg 1.5 – 2.5 mmol/L

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6
Q

Excess fluids

A

UNCOMPENSATED INTAKE
Causes of Imbalance
*Excessive IVF
administration
*Excessive water
consumption
(polydipsia)

INADEQUATE OUTPUT
Heart failure
*Endocrine disturbances
*Liver failure
*Renal impairment
*Anuria (no urine output) or
oliguria (scant urine output)
*SIADH (syndrome of
inappropriate antidiuretic
hormone secretion)

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7
Q

Excess fluids symptoms

A

Neurological compromise
Headache, seizures, LOC
Respiratory
Pulmonary congestion
Cardiovascular
Bounding pulse, tachycardia, ECG
changes
GI changes
Nausea, vomiting, anorexia
Edema
peripheral - interstitial
third spacing - transcelullar

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8
Q

Oedema

A

Oedema is the abnormal collection of excess fluid in the
interstitial compartment

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9
Q

Third place fluid

A

A shift of body fluids into potential body spaces
(transcellular) such as the pleural, peritoneal
(ascities), pericardial or joint cavities; the bowel; or
the interstitial space.
Fluid moves out of the intravascular spaces
(plasma) to any of these spaces.
Cause:
A decrease in the colloid osmotic pressure
An increase in the permeability of the capillary
membrane
A severe burn, a bowel obstruction or
hypoalbuminaemia

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10
Q

Excess interventions

A

Restrict fluid intake +/- sodium
intake
*Close fluid balance monitoring
*Add or increase diuretics
*?Dialysis

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11
Q

Who is at defitcit risks

A

Comorbidities, particularly GI, renal,
neurological or cardiac diagnoses
Children
Elderly
Confused
Hospitalised
NBM/GI disturbance
Diuretics
IV therapy - blood products
Athletes

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12
Q

Deficit imbalance

A

INADEQUATE INTAKE
*Nausea / anorexia
*Difficulty swallowing
*Lack of water access
*Diminished thirst drive
*NBM / intubation

UNCOMPENSATED LOSS
Diarrhoea
*Vomiting
*Polyuria
*Haemorrhage
*Burns

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13
Q

Deficit Signs & Symptoms

A

Dry oral cavity / furrowed tongue
Thirst
Reduced skin turgor
Cool, pale skin, delayed capillary refill
Weak, rapid pulse
Decreased blood pressure
Orthostatic hypotension

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14
Q

Deficit interventions

A

Losses
Treat GI disturbances
Reduce diuretics
Stop bleeding

Intake
Oral rehydration
IV rehydration

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15
Q

IV fluids: Isotonic: (similar osmolality)

A

Benefits
Sustain extracellular fluid volume
Hydration, maintain electrolytes
Increase BP
Trauma, surgery, burns
Risk
Risk of fluid overload
Example
0.9% Sodium Chloride

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16
Q

IV fluids: Hypotonic (lower osmolality)

A

Benefits
Rehydrates cells
Hypernatremia or other hyperosmolar conditions
Risk
Sudden shift of fluid from blood vessel to the cells –
cardiovascular collapse
Can cause cellular swelling- monitor for changes in cognition
Example
0.45% Sodium chloride

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17
Q

IV fluids: Hypertonic (higher osmolality)

A

Benefits
Decrease oedema, increase urine output
Stabilize BP
Maintain fluid balance
Can temporarily be used to treat hypovolemia if plasma
expander is not available
Risk
pulls electrolytes and fluids from cells
Fluid overload
Cardiac and renal failure
Example
3% Sodium Chloride

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18
Q

Colloids

A

Plasma expanders
Contain large insoluble particles such as gelatine, used if
crystalloids don’t improve blood volume

Blood
Acts like hypertonic solution drawing fluid out of cells increasing
ECF
Longer lasting effect than crystalloids
Used in emergencies – shock, circulatory collapse, hypotonic
dehydration
Increased risk of reaction

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19
Q

Osmolarity weight

A

Osmolality is measuring the
number of osmoles in a weight
(kg) of solvent.

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20
Q

Osmolarity Volume

A

Osmolarity is measure the
number of osmoles in a volume
(L) of solvent

ie: the concentration of solutes
in a solution

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21
Q

What does fluid do? (s, t)

A

Solvent
Transport (nutrition, excretion, non-electrolytes & electrolytes)

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22
Q

What does fluid do? (T, L)

A

Temperature regulation
Lubrication

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23
Q

What does fluid do? (FM&CF, BP)

A

Facilitates metabolism & cellular function

Blood pressure

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24
Q

What does fluid do? (FD&E)

A

facilitates digestion & elimination

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25
Where it is in the body?
2 major fluid compartments in the body intracellular (ICF 28LP) extracellular (ECF 14L)
26
4 ECF compartments
intravascular intersitital lymph transcellular
27
Solute
substances dissolved in solution
28
Non electrolyte
Urea, glucose, creatinine, protein
29
Electrolyte
– Substances whose molecules dissociate or split into ions when placed in water – Positively charged ion – cation (K+, Na+, Ca2+, H+) – Negatively charges ion – anion (Cl-, HCO3, PO43-)
30
Fluid Movement Concepts
Osmosis and Diffusion & Hydrostatic pressure
31
Fluid Movement
Osmotic Pressure (no net energy use)
32
Osmotic Pressure
power of solution to draw H2O through selectively permeable membrane Higher solute concentration exerts higher osmotic pressure Expressed as either osmolality or osmolarity
33
Fluid Exchange Across the Walls of Capillaries
34
Fluid Movement
Filtration pressure (no net energy use): Hydrostatic pressure Oncotic pressure albumin pressure
35
albumin pressure
key plasma protein creating osmotic pull
36
Filtration pressure
pressure in compartment that results in movement of fluid and solutes – made up of the net of next 2 pressures..
37
Hydrostatic pressure:
pressure exerted by fluid within a closed system on the walls of container in which it is in. Or “push
38
Oncotic pressure:
By proteins Or “pull”
39
Tonicity
Refers to osmolality of a solution Isotonic: Hypertonic: Hypotonic:
40
Isotonic
same osmolality of body fluids. NS (0.9%NaCl) RL
41
Hypertonic
higher osmolality than body fluids. D5NS, 3%NaCl, D5, RL
42
Hypotonic
lower osmolality than body fluids. H2O, 1/2NS (0.45%NaCl)
43
Maintaining Homeostasis
endocrine system – CV – lungs
44
Maintaining Homeostasis
kidneys – primary regulator of fluids and electrolytes – by regulating H2O and lyte excretion. – big role in acid-base balance by excreting H+ & retaining HCO3
45
Maintaining Homeostasis
GI system – Hormones
46
Fluid Imbalances
Hypovolemia * Hypervolemia
47
Fluid Imbalances
Dehydration – water loss without ‘lyte loss * Over hydration – water intoxication - more water than ‘lytes. Low serum osmolality and low Na levels
48
Solute Concentration
Osmolality: determined by total solute concentration within a fluid compartment.
49
Solute Concentratio
Na+ biggest determinant of serum osmolality. – K+ glucose, & urea determine osmolality of ICF. – Plasma proteins: cause colloid or osmotic pressure
50
What is an electrolyte?
H2+O- & Na+Cl- into soln of free ions+ Na+ attracted to O- Cl- attracted to H2+
51
Electrolyte Regulation
Most ‘lytes come from dietary intake & are excreted in urine. – Na+ & Cl not stored-must be consumed daily. – K+ & Ca+ are stored in cells and bones.
52
Sodium
Na+: 135-145mEq/L * Major ECF cation * Major functions: – Water balance – Transmission of nerve impulses * N for Neuro * Tx ?
53
Potassium
K+: 3.5-5.0mEq/L * Major cation of ICF * Major function: – Electrical conduction of nerve impulses-cardiac conduction – Cell metabolism (glycogen & glucose) * Body more sensitive to small changes in serum K+ than other electrolytes * K for Kardiac ! * Tx ?
54
Fluid Movement
Active transport (energy used) * is important in maintaining differences in Na+ & K+ – Usually Na+ concn are higher in ECF and K + is higher in ICF. – To maintain this, the Na+ K+ pump is activated, moving Na+ from cells and K+ into cells.
55
Calcium
Ca++: 8.5-10.5 mg/dl * Major functions: 1% in ECF – Normal skeletal muscle, smooth muscle, & cardiac muscle contraction; blood clotting * In through diet. Needs Vit. D. to be absorbed
56
Phosphate
HPO42-: 1.6 – 2.9 mEq/L * Major functions: – Forms bones and teeth – Metabolises carbs, protein, & fat – Cellular metabolism: ATP and DNA – Muscle, nerve, and RBC function – Acid-Base balance – Regulates Ca levels
57
Magnesium
Mg: 1.5-2.5 mEq/L * Major functions: – Operating Na-K pump-use of ATP (energy) – Relaxing muscle contractions – Transmitting nerve impulses – Regulates cardiac function – Blood clotting – Protein & DNA synthesis
58
Bicarbonate: HCO3
Primary function: – Acid-Base balance: essential part of carbonic acid- bicarbonate buffering system. * ECF regulated by kidneys. Kidneys regenerate and reabsorb if needed.
59
Factors affecting fluids/lytes/AB
Age: – Elderly: thirst response blunted. – Nephrons less able to conserve water – Increased risk of dehydration. – Increased likelihood of heart diseases, impaired RF, multiple meds. * Gender/Body Size: – Fat cells have no H2O. – Women have more fat = less body water.
60
Factors Affecting
Environmental Temp: – Illness and strenuous activity – Salt and water lost with sweating * Lifestyle: – Smoking, ETOH ... * Diet: – anorexia, bulimia, malnourishment-low albumin, edema, acidosis * Exercise: – weight-bearing-Ca balance * Stress: – increased cellular metabolism
61
Nursing Management
Output: – urinary, vomitus, liquid faeces, tube drainage, wound drainage * Can be totaled at end of shift (8-12 hours). Then added and totaled at 24 hours * Labs: – electrolytes, FBC, haematocrit, albumin, osmolality, urine pH, urine specific gravity, ABGs, 24o urine (GFR)
62
Take homes on electrolytes:
Many are essential minerals * They control osmosis of water between compartments. * They help maintain the acid-base balance required for normal cellular activities * They carry electrical current, which allows production of action potentials and graded potentials and controls secretion of some hormones and neurotransmitters.
63
Types of Fluid Replacement
Blood transfusions: – affect O2 carrying capacity of blood. * Blood groups: A,B,AB,O * Rh factor * Typing and Crossmatching: – Type: ABO & Rh factor; Xmatch: antigens * Blood always given with NS hanging too
64
Types of Fluid Replacement
Colloids – Albumin, FFP – Plasma protein fraction * Colloid Substitutes – Dextran – Hetastarch * Blood Transfusions – Packed Red Blood Cells – Whole Blood
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Types of Fluid Replacement