Fluids Fr Flashcards

(20 cards)

1
Q

Definition of a fluid

A

A material that is unable to sustain an applied shear load at rest

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2
Q

Re and flow characteristics

A

0<Re<1 - extremely viscous laminar flow dominated by viscosity
1<Re<2000 - Laminar flow, both viscous and inertial terms important
Re>2000 - Turbulent flow, viscosity relatively unimportant
Critical Re for onset of turbulence depends on geometry and surface features

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3
Q

Blood flow characteristics

A
  • most blood flow is laminar
  • might be turbulent in aorta at peak systole, at stenosis
  • turbulent when heart valves leak and when using a sphygmomamnometer
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4
Q

Turbulent shear stress

A
  • density x product of mutually perpendicular components of velocity
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5
Q

Sphygmomanometry

A
  • the measuring of blood pressure
    Method:
  • place cuff around arm
  • rest arm on surface just below heart level
  • place stethoscope on hollow of elbow over brachial artery
  • inflate cuff to pressure where blood does not flow
  • release until K sounds are heard - systolic pressure
  • release until no sound is heard - diastolic pressure
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6
Q

Viscosity

A
  • the constant of proportionality linking shear stress to shear strain rate
  • fluids that exhibit this behaviour are known as Newtonian fluids
  • viscosity can vary within fluids with change in temperature due to interactions at smaller length scales
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7
Q

Variation in fluid behaviour for different fluid types

A

Plastic fluids
- high viscosity at low shear rates but ‘softens’ at higher shear rates’
Newtonian fluids
- constant viscosity (shear stress proportional to shear rate)
Dilatant fluids
- low viscosity at low shear rates but ‘stiffens’ at higher shear rate
Frictionless
- no resistance to applied shear / no viscosity

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8
Q

Hematocrit definition

A

Percentage of blood volume occupied by red blood cells (typically 50%)

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9
Q

Blood fluid properties

A
  • inhomogeneous
  • plasma (no hematocrit) is a Newtonian fluid with viscosity close to water
  • as hematocrit increases viscosity increases
  • at low shear rates RBCs can clump together (Rouleux formation) - this increases viscosity at low shear rates
  • For 50% hematocrit viscosity is relatively constant in range 1 - 100 s^-1 (4 x thicker than water)
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10
Q

Fahreus lindquist effect

A
  • as blood of constant haematocrit flows into smaller tubes a larger proportion of the volume is close to walls
  • this results in a cell free layer close to walls, reducing overall haematocrit in tube
  • viscosity of blood will therefore also decrease as diameter decreases
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11
Q

Affects of shear stress on RBCs and Platelets

A

10 - 100 dyne/cm2: damages adhered RBC, platelets activated
> 500 dyne/cm2 turbulent shear stress: loss of bioconcavity
>3000 dyne/cm2: haemolysis (RBC rupture)

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12
Q

Viscous vs inviscid flow

A

Inviscid = viscous effects neglected
Inviscid flow assumed when fluid flow is far from a boundary (usually external to a body)

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13
Q

Incompressible vs compressible flow

A
  • when variation of density is small we assume flow is incompressible
  • this is quantified by a Mach number < 0.3
    Ma = u/a where u is velocity of flow relative to medium and a is speed of sound in medium
  • speed of sound in water is 1484m/s and resulting flows Ma«0.3
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14
Q

Ratio of distal and proximal diameter
Ratio of distal and proximal area
Ratio of distal and proximal velocity
Ratio of distal and proximal Reynolds number

A
  • D(d) = 0.8D(p)
  • A(d) = 1.28A(p)
  • v(d) = 0.781v(p)
  • Re(d) = 0.625Re(p)
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15
Q

Flow development:
- temporal
- spatial

A

Temporal: refers to time it takes for a flow to become fully developed
Spatial: when flow is disturbed a fully developed flow is not observed immediately, space is required for the viscous effects at the wall to act on the fluid to produce a parabolic profile
- entrance length for flow to become fully developed is given by:
- L = 0.03 D Re

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16
Q

Why (experimentally) we might not see a parabolic velocity profile in a tube

A

Flow could be:
- temporally undeveloped (not enough time passed under constant pressure gradient)
- spatially undeveloped (not far enough away from flow disturbance for flow to be parabolic)
- flow is turbulent

17
Q

What is the equation for Reynolds number

A

See equation sheet

18
Q

What is the equation for poiseulle flow

A

See equation sheet

19
Q

Derive poiseuille flow

20
Q

what is the womersley and strouhal number

A
  • characterise periodicity of flow
  • womersley number applies to straight tubes
  • see equation sheet for equations