Forget me not Flashcards
When do we see positive Coombs?
Warm AIHA
Drugs that prolong QT?
Erythromycin Antihistamines Anticholinergics Antiarrthmics - Quinidine, Sotalol TCAs Fluroquinolones Chloroquine, Mefloquine, Haloperidol, Risperidone, Methadone, and HIV protease Inhibitors.
Indications for C section
Cephalopelvic disproportion Fetal Malpresentation Nonreassuring EFM strip Placenta previa Infxn - HIV or Active vaginal herpes Uterine scar
OCD first line TX
SSRI
When do we do Endoscopy?
Alarm sx’s: Wt loss, blood in stool, anemia
When do we hear succussion splash on abdominal auscultation?
Gas and fluid in obstructed organ Gastric Outlet syndrome Diaphragmatic Hernia Bronchopleural fistula Pyloric stenosis
What do we see in Cushing’s syndrome
Central Obesity Fat accumulation in cheeks, dorsocervical (hump behind neck), supraclavicular fat pads Purple striae Thinned skin Proximal muscle weakness HTN Glucose intolerance Skin hyperpigmentation (ACTH excess) HypoKalemia
Dx for Cushing’s?
24 hour cortisol excretion
Late evening salivary cortisol
Low dose dexamethasone suppression test
Acid base disturbance seen in Cushing syndrome?
Metabolic Alkalosis
Is osteoid osteoma benign or malignant?
Benign
Describe presentation of osteoid osteoma
Limb pain worse at night Responds to NSAIDs Unilateral pain Second decade of life Limp and point tenderness
Age for growing pains?
2-12 years
What does stridor sound like and what is pathophysiology?
Squeaky, whistlelike sound
Turbulence b/t supraglottis and trachea
Breath sounds in narrowing/congestion of bronchioles
Rales
Rhonchi
Wheezing
Causes of pediatric stridor?
Croup Foreign body aspiration Anatomic abnormalities - Laryngomalacia - Vascular ring
MCC of inspiratory stridor in kids?
Laryngomalacia
- increased laxity of supraglottic structures
Inspiratory stridor worse w supine position, crying or feeding, Improves in prone position, 4-8 months?
Laryngomalacia
Dx for laryngomalacia
flexible laryngoscopy - collapse of supraglottic structures w/inspiration and omega shaped epiglottis
When do we do CT neck in peds?
Retropharyngeal abscess
Tx for laryngomalacia?
Self resolves by 18 months
How is overexpression of HER2 assessed?
Oncogene amplification by FISH Immunohistochemical staining (IHC)
Why is HER2 assessment imp in breast cancer?
Tx with trastumab = Herceptin
- Targets HER2/neu
- Adjuvant anthracycline tx (doxarubicin, danarubicin)
JAK2 mutation ass’d with?
Polycythemia vera
How does late coarctation of aorta present?
Asymptomatic HTN
Chest pain, claudication, HA, Epistaxis, HF
Severe - Aortic dissection
