UW 12 Flashcards

(59 cards)

1
Q

AE’s of Lithium

A
GI distress
Nephrotoxic
Hypothyroidism
Leukocytosis
Tremors
Acne
Psoriasis flares
Hair loss
Edema
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2
Q

MCC death Dialysis

A

Cardiovascular

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3
Q

Nerve that does knee extension and hip flexion

A

Femoral Nerve

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4
Q

Provides sensation to anterior thigh and medial leg

A

Femoral Nerve

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5
Q

Adduction of leg and sensation of medial thigh

A

Obturator Nerve

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6
Q

Tx of infertility for premature ovarian failure

A

IVF w donor oocyte only option

No viable oocytes

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7
Q

Cardiac amyloidosis

A

Unexplained CHF
Echo = increased LV thickness, normal LV cavity
Low voltage EKG

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8
Q

Amyloidosis Pathophys

A

Extracellular deposit of insoluable polymeric protein fibrils in tissues and organs

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9
Q

Amyloidosis secondary due to?

A
Inflammatory arthritis 
Chronic Infxn
IBD
Malignancy
Vasculitis
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10
Q

Amyloidosis Presentation

A
Asymptom proteinuria 
Nephrotic syndrome
Hepatomegaly
Peripheral Neuropathy
Visible organ enlargement
Bleeding diathesis
Waxy thickening, skin bruising
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11
Q

Dx for Amyloidosis

A

Tissue Bx

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12
Q

What is a torus palatinus

A
Growth on hard palate
Fleshy, immobile mass
Benign
Midline suture 
Genetic and environmental
Ulcerates w trauma 
Heals slowly
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13
Q

Tx for torus palatinus

A

Surgery

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14
Q

What does aromatase do

A

Converts androgens into estrogens

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15
Q

Presentation of aromatase deficiency

A
Masculinization of mother resolves w delivery
Virilization
Normal internal genitalia
Ambigious external genitalia
Clitoromegaly
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16
Q

Presentation of aromatase deficiency later in life

A

Delayed puberty
osteopororosis
Undetectable estrogen
Polycystic ovaries

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17
Q

Labs with aromatase deficiency

A

High FSH/LH

Low estrogen

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18
Q

McCune Albright triad

A

Cafe au lait spots
Polyostotic fibrous dysplasia
Autonomous endocrine hyperfnc
- Precocious puberty

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19
Q

Kallman syndrome Presentation and Labs

A
46 XX
Hypogonadotropic hypogonadism
Anosmia
Delayed puberty
Normal internal reproductive organs
Low or absent LH and FSH
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20
Q

Tx for premature ovarian failure infertility

A

IVF with donor oocytes

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21
Q

Premature ovarian failure

A
< 40 yoa
Amenorrhea
Hypoestrogenism
Increased FSH and LH
Low Estrogen
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22
Q

Management for threatened abortion

A

Reassurance and outpatient f/u after assess fetus w US

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23
Q

Tx for asymptomatic PVCs

A

Observation

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24
Q

Tx for symptomatic PVCs

A

Beta blockers

Amiodarone

25
Langerhans cell histiocytosis Presentation
Solitary, lytic long bone lesion Painful, tender swelling Hypercalcemia
26
Tx for HCV
Peg IFN | Ribavarin
27
Anticholinergic excess si/sx's
Red as a beet - flushing Dry as a bone - anhidrosis/dry mouth Hot as a hare - hyperthermia Blind as a bat - vision changes/mydriasis Mad as a hatter - delirium/confusion Full as a flask - urinary retention/constipation
28
Parkinson drug with anticholinergic excess sx's
Trihexyphenidyl | Benztropine
29
Presentation of amebic liver abscess
``` Hx of travel Dystentery RUQ pain Single cyst - right lob of liver Bloody diarrhea Pleuritic like pain - if on surface ```
30
Dx for E.Histolytica infxn
Stool for trophozoities Serology Liver imaging
31
Hydatid cyst
Echinococcus granulosos | Dog contact
32
Hepatic adenoma
Solid lesion
33
What is another name for pseudotumor cerebri
Idiopathic intracranial HTN | IIH
34
Meds that cause IIH
Vit A and derivatives GH Tetracyclines
35
MEN Type I
Primary PTH Enteropancreatic tumors Pituitary tumors
36
MEN 2A
Medullary thyroid cancer Phaeo Parathyroid hyperplasia
37
MEN 2B
1.MTC 2. Pheo 3.Mucosal/intestinal neuromas Marfanoid
38
Extra renal complications of ADPKD
1. Hepatic cysts 2. Valvular heart dz - MVP, AR 3. Colonic diverticula 4. Abd wall and inguinal hernia
39
Isolated Systolic HTN (ISH) Pathophysiology
Decreased elasticity of arterial wall -> increased SBP (no change in DBP) Rigid arteries with aging = reduces compliance, and ability to dampen SBP
40
Tx for ISH
Low dose thiazide ACE CCB - long acting
41
What is PANDAS
Pediatric AI Neuropsychiatric disorder
42
How does PANDAS present
Recent GAS infxn Acute onset OCD Tic disorder
43
What heart change seen in cor pulmonale
TR Loud P2 RV S3
44
Dx with cath for cor pulmonale
Elevated PA SBP | > 25 mmHg
45
What does PCWP estimate
LV EDV
46
What is presentation of Necrolytic Migratory Erythema (NME)
Erythematous papules/plaques Coalesce Form large, painful, inflammatory blisters +/- crusting and central clearing
47
Presentation of glucagonoma
``` DM NME Wt loss Diarrhea Anemia ```
48
Glucagonoma v Gastrinoma
Both: diarrhea, wt loss, anemia, abd pain | Only glucagonoma ass'd with DM and NME
49
How to confirm dx of glucagonoma?
Glucagon > 500 pg/mL
50
NPV relationship with pretest probability
Pt with high probability of having dz = LOW NPV | Pt with low probability of having dz = HIGH NPV
51
Do sensitivity and specificity vary with pretest probability
NO
52
What measures probability of being free of dz if test result is negative
NPV
53
Management of DM pt w acute pyelonephritis
Parenteral Abx 48-72 hrs | Clear response - change to oral abx for 10-14 days
54
What is the Ghon complex
Tubercle Ass'd LA Reactivation TB = upper lobe infiltrate
55
Comorbidities of panic disorder
``` Major Depression Bipolar Agoraphobia Substance Abuse Increased SI/attempts ```
56
Disorders ass'd with Vitiligo
``` Pernicious Anemia Grave's Type 1 DM Primary adrenal insufficiency Hypopituitarism Alopecia areata ```
57
Where do we see pleural plaques
Bronchogenic carcinoma
58
What is the MC malignancy ass'd with asbestos
Bronchogenic Carcinoma | then, mesothelioma
59
What vitamin reduces morbidity and mortality in measles
Vit A