G-Protein Linked 2nd Messengers Flashcards

(14 cards)

1
Q

Alpha1

A

Q
Increase vascular smooth muscle contraction
Increase pupillary dilation (mydriasis)
Increase intestinal & bladder sphincter contraction

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2
Q

Alpha2

A
I
Decrease sympathetic outflow
Decrease insulin release
Decrease lipolysis
Increase platelet aggregation
Decrease aqueous humor production
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3
Q

Beta1

A

S
Increase HR & contractility
Increase renin release
Increase lipolysis

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4
Q

Beta2

A
S
Vasodilation, bronchodilation
Decrease uterine tone
Increase lipolysis
Increase insulin release
Increase aqueous humor production
Relax ciliary muscles
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5
Q

Beta3

A

S
Increase thermogenesis in skeletal muscle
Increase bladder relaxation
Increase lipolysis

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6
Q

M1

A

Q

Higher cognitive functioning

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7
Q

M2

A

I
Decrease heart rate
Decrease contractility of atria

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8
Q

M3

A
Q
Increase exocrine gland secretions
Increase bronchoconstriction
Increase bladder contraction
Increase gut peristalsis
Increase insulin release
Miosis & accommodation
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9
Q

D1

A

S

Relaxes renal vascular smooth muscle

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10
Q

D2

A

I
Brain receptor
Inhibits indirect pathway of striatum

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11
Q

H1

A
Q
[Allergies]
Increase nasal & bronchial mucus production
Increase vascular permeability
Increase contraction of bronchioles
Pruritis, pain
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12
Q

H2

A

S
[GERD]
Increase gastric acid secretion

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13
Q

V1

A

Q

Increase vascular smooth muscle contraction

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14
Q

V2

A

S
[Vasopressin]
Increase H2O reabsorption at collecting ducts of kidney

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