Gas Exchange (3) Flashcards

1
Q

What is pulmonary ventilation?

A

The volume of air breathed in and out per minute

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2
Q

What is alveolar ventilation?

A

The volume of air exchanged between atmosphere and alveoli per minute (represents new air available for gas exchange with blood)

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3
Q

What is anatomical dead space?

A

Inspired air that remains in the airways where it is not available for gas exchange

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4
Q

What increases pulmonary ventilation and what is more advantageous?

A

Increase depth (tidal) and rate . Due to dead space , deep breathing is more advantageous.

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5
Q

What 2 things does the transfer of gases between the body and atmosphere depend on and explain them?

A

Ventilation- the rate at which gas is passing through the lugs
Perfusion-the rate at which blood is passing through the lugs

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6
Q

What is alveolar dead space?

A

Ventilated alveoli which are not adequately perfused with blood

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7
Q

What is physiological dead space?

A

Anatomical dead space and the alveolar dead space

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8
Q

What matches airflow to blood flow?

A

Local controls act on smooth muscles of airways and arterioles

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9
Q

What 4 factors influence the rate of gas exchange across the alveolar membrane?

A

1) Partial pressure gradient of O2 and CO2
2) Diffusion coefficient for O2 and CO2
3) Surface area of alveolar membrane
4) Thickness of alveolar membrane

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10
Q

What is Daltons law of partial pressure?

A

The total pressure exerted by a gaseous mixture = sum of the partial pressures of each individual component in the gas mixture

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11
Q

What determines the pressure gradient for a gas?

A

Partial pressure of that gas

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12
Q

What is the pressure of inspired air?

A

atmospheric pressure - water pressure

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13
Q

What is the diffusion coefficient?

A

The solubility of gas in the membrane

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14
Q

Which gas has a higher diffusion coefficient?

A

The diffusion coefficient for CO2 is 20 times that of O2

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15
Q

What is Fick’s law of diffusion?

A

The amount of gas that moves across a sheet of tissue in unit of time is proportional to the area of the sheet but inversely proportional to its thickness

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16
Q

How does surface area and a thin membrane affect gas exchange ?

A

Lungs provide a very large surface area with thin membranes to facilitate effective gas exchange. Airways divides repeatedly and small airways form out pockets to increase surface area

17
Q

What are the non-respiratory functions of respiratory system?

A

1) route for water loss and heat elimination
2) Enhances venous return
3) help maintain normal acid-base balance
4) Enables speech, singing
5) Defends against inhaled foreign matter
6) Removes,modifies,activates/inactivates various materials passing through the pulmonary circulation
7) nose serves as the organ of smell

18
Q

What is partial pressure?

A

The pressure that gas that would exert if it occupied the total volume for the mixture in the absence of other components

19
Q

What Is alveolar gas equation?

A

PAO2= PIO2 - (PaCO2/0.8)
PAO2- partial pressure of alveolar air
PiO2- partial pressure of O2 in inspired air
PaCO2- partial pressure of CO2 in arterial blood