Gastroenterology

Question 1

Hepatitis B status:
- Anti HBs positive. All other tests negative

Answer 1

Previous immunisation

Question 2

Hepatitis B status:
- Anti HBc positive. HBsAg negative

Answer 2

Previous infection not a carrier

Question 3

Hepatitis status: Anti Hbc IgG positive, HbsAg positive. Negative anti HbC IgM and anti Hbs

Answer 3

Chronic Hep B infection

Question 4

Treatment of recurrent C Diff within 12 weeks of symptom resolution

Answer 4

Fidaxomicin

Question 5

Investigation of choice for suspected perianal fistulae

Answer 5

MRI pelvis - used to etermine whether the fistula is simple or complex

Question 6

Antibodies present in Primary biliary cholangitis

Answer 6

Anti mitochondrial antibodies

Question 7

Management of primary biliary cholangitis

Answer 7

Urseodeoxycholic acid

Question 8

What is barrats oesophagus?

Answer 8

Metaplasia of the lower oesophageal mucosa with the squamous epithelium being replaced by columnar epithelium

Question 9

What is the most common extra intestinal feature in crohns disease and ulcerative colitis?

Answer 9

Arthritis

Question 10

In Crohns and UC which extrarticular manifestations are related to disease activity.

Answer 10

Arthritis (asymmetrical)
Erythema nodosum
Episcleritis
Osteoporosis

Question 11

In crohns and UC what extracurricular manifestations are unrelated to disease activity

Answer 11

Arthritis (symmetrical)
Uveitis
Pyoderma gangrenosum
Clubbing
Primary sclerosing cholangitis

Question 12

First line test for H Pylori

Answer 12

Urea breath test.

Question 13

What test can be used to confirm H Pylori eradication

Answer 13

Urea breath test

Question 14

What cancer are yoy at increased risk of if you have coeliac disease

Answer 14

Enteropathy associated T cell lymphoma of the small intestine

Question 15

What is the double duct sign on MRCP and what does it mean?

Answer 15

Dilatation of the common bile duct and the pancreatic duct – indicitive of pancreatic cancer

Question 16

Investigation of choice for suspected pancreatic cancer

Answer 16

High resolution CT scanning

Question 17

First line to achieve remission is crohns disease

Answer 17

Steroids

Question 18

First line to maintain remission in crohns disease

Answer 18

Azathioprine

Question 19

Most common cause of hepatocellular carcinoma in the UK

Answer 19

Hepatitis C

Question 20

Are granulomas seen in crohns or UC

Answer 20

Crohns

Question 21

What is melanosis coli associated with?

Answer 21

Laxative abuse

Question 22

Are goblet cells associated with crohns or UC?

Answer 22

Crohns

Question 23

What is peutz jeghers syndrome

Answer 23

Autosomal dominant condition characterised by numerous hamartomatous polyps in the GI tract. Also associated with pigmented frckles on the lips, face, palms and soles.

Question 24

Inheritence pattern of hereditary haemachromatosis

Answer 24

Autosomal recessive

Question 25

Treatment for wilsons disease

Answer 25

Penicillamine

Question 26

HLA subtype in coeliac disease

Answer 26

HLA DQ2 and HLA DQ8

Question 27

When do PPIs have to be stopped prior to GI endoscopy

Answer 27

2 weeks before an upper GI endoscopy

Question 28

Is total iron binding capacity low or high in Iron deficiency anaemia?

Answer 28

High

Question 29

Is total iron binding capacity low or high in anaemia of chronic disease?

Answer 29

Low or normal

Question 30

Blood tests for monitoring haemachromatosis

Answer 30

Transferrin saturation (below 50%) and serum ferritin (below 50)

Question 31

Antibodies in autoimmune hepatitis

Answer 31

ANA Anti smooth muscle antibodies

Question 32

What malignancy is associated with H Pylori

Answer 32

MALT Lymohoma Mucosa associated lymphoid tissue

Question 33

Type of oesophageal cancer more likely to develop in patients with a hostory of GORD or Barrets oesophagus

Answer 33

Adenocarcinoma

Question 34

Investigation for local staging of oesophageal cancer

Answer 34

Endoscopic USS

Question 35

What type of oesophageal carcinoma is seen more commonly in patients with achalasia

Answer 35

Squamous cell

Question 36

Where is the oesophagous do you get adenocarcinoma

Answer 36

Lower third

Question 37

Where in the oesophagus do you get Squamous cell carcinoma

Answer 37

Upper two thirds