Gastroenterology + hepatology Flashcards
Which herpesvirus can cause splenomegaly?
HHV4 (EBV)
Investigations for suspected Hirschsprung’s?
Barium enema
Rectal manometry
Rectal suction biopsy
Presentation of B6 deficiency in neonates
Seizures
Takes 2-6 mins for EEG to normalise after pyridoxine administration
Features of infantile beri beri
Thiamine deficiency Hoarse cry (laryngeal nerve paralysis) Pseudomeningitis
What happens in wet beri beri?
High output cardiac failure
Presentation of vitamin E deficiency in neonates
Haemolytic anaemia Peripheral neuropathy Acanthocytes Cerebellar signs Retinitis pigmentosa
Which IBD is primary sclerosing cholangitis more common in?
Ulcerative colitis
Presents with chronic cholestatic liver disease, structural heart disease, skeletal abnormalities, renal abnormalities, poor growth and facial dysmorphism?
Alagille’s syndrome
Initial investigations in suspected coeliac?
Stool microscopy
Serum total IgA
Small bowel biopsy
Coeliac serology screen
Protein results in autoimmune hepatitis?
High total protein
Low serum albumin
= large amount of IgG
Most effective agents in maintaining remission in Crohn’s disease?
6-mercaptopurine
Methotrexate
What is Sandifer’s syndrome?
Association between reflux and abnormal head posturing
Biochemical features of tumour lysis syndrome
High potassium
High phosphate
High urate
Low calcium
Presents at birth with intractable, secretory, watery diarrhoea and severe Malabsorption
Congenital microvillus atrophy
Presents with malabsorption, protein losing enteropathy, oedema and steatorrhoea/diarrhoea
Congenital intestinal lymphangiectasia
