Pharmacology

Question 1

First line drugs for absence seizures

Answer 1

Sodium valproate

Ethosuximide

Question 2

Antiepileptics which can worsen absence seizures?

Answer 2

Carbamazepine

Vigabatrin

Question 3

Which salicylate level represents toxicity?

Answer 3

750mg/L

Question 4

Best antibiotics for a neonate with suspected listeria

Answer 4

Ampicillin + gentamicin

Question 5

Causes yellow and blurred vision

Answer 5

Digoxin

Question 6

Anti tubercular treatment which causes visual problems (loss of acuity, colourblindness, restriction of visual fields)

Answer 6

Ethambutol

Question 7

Vitamin which causes papilloedema (pseudotumour cerebri)

Answer 7

Vitamin A

Question 8

Vitamin which causes blurred vision with band keratopathy

Answer 8

Vitamin D

Question 9

Treatment options for vWD

Answer 9

Factor VIII concentrate

Desmopressin

Question 10

Effects of carbamazepine overdose

Answer 10

Diplopia
Nystagmus
Ataxia
Hyponatraemia
Hepatotoxicity
Peripheral neuropathy

Question 11

Side effects of azathioprine

Answer 11

Bone marrow suppression + GI upset

Question 12

Side effects of methotrexate

Answer 12

Mucositis
Myelosuppression
Hepatotoxicity
Pulmonary fibrosis

Question 13

Most likely to cause melanosis coli

Answer 13

Senna and dantron

Question 14

Renal complications of glue sniffing

Answer 14

Proteinuria
Distal renal tubular acidosis
Renal calculi

Question 15

Drugs causing gynaecomastia

Answer 15

Ciclosporin
Digoxin
Spironolactone