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Flashcards in General Deck (48):
0

How do enzymes work

Lower free energy of activation

1

What does the Michaelis menten equation describe

How rxn velocity varies with substrate concentration

2

MM kinetics follow a ___ curve?

Hyperbolic curve

3

What are factors wc can affect the rxn rate

Substrate conc, temp, pH

4

Lineweaver burke plot is used for

Calculated Km and Vmax; determines mechanism of action of enzyme inhibitors

5

Precursor of arachidonic acid

Linoleic acid

6

Alcohol+ diacylglycerol/ spingosine via phosphodiester bond

Phospholipid

7

Spingosine and Fatty acid

Ceramide

8

Ceramide and gluctose or galactose

Cerebroside

9

Ceramide and oligosaccharide

Globosidr

10

Ceramide and N acetylneuramic acid

Ganglioside

11

Ceramide and sulfated galactose

Sulfatides

12

3 main kinds of eicosanoids

Porstaglandin, thromboxane, leukotrienes

13

Amino acid structure

Caboxyl, amino group, unique side chain

14

Smallest amino acid

Glycine

15

Largest amino acid

Tryptophan

16

Amino acid used in the 1st step of heme synthesis

Glycine

17

Major inhbitory NT in spinal cord

Glycine

18

AA that carries N from peripheral tissues to the liver

Alanine

19

Precuror of niacin, serotonin and melatonin

Tryptophan

20

Precursor for homocysteine

Methionine

21

An imino acid

Proline

22

To cysteines form

Custine

23

Major carrier of nitrogen from the peripheral tissues to the liver

Glutamine

24

Precursor for GABA and glutathione

Glutamate

25

Used in diagnosis of folic acid deficiency

N- formiminoglutamate excretion test

26

Precursor of creatinine, urea and nitric oxide

Arginine

27

All amino acids are chiral except for

Glycine

28

Chemical compound that has a total net charge of zero

Zeitteriob

29

Condotionally non essential amino acids

Arginine, histidine

30

Most common secondary structure of proteins

Alpha helix

31

Minor transporternof hgb in bloof

Hemoglobin (carbaminoHb)

32

HgB form with high oxygen affinity? Taut or Relaxed

Relaxed

33

Heme protein in heart and skeletal muscle

Myoglobib

34

Curve followed by Hgb

Sigmoidal

35

Deoxy form of HgB has a greater affinity for protons than does oxyhemoglobin

Bohr effect

36

Stabilizes T structure of Hgb by forming additional salt bridges that must be broken prior to conversion to the R state

2,3 BPG

37

Oxidized form of Hgb (Fe3)

Methemoglobin

38

Chocolate cyanosis

Methemoglobinemia

39

Most abundant protein in body

Collagen

40

Most common form of collagen

Type I

41

Amino acid sequence of collagen

Gly-X-Y ; x: proline= kinking; y: hydroxyproline or hydroxylysine

42

HCl is produced by what cells

Parietal cells

43

Pepsinogen is produced by

Chief cells

44

All amino acids must transfer their amino groups to a ketoglutarate to from GLUTAMATE except

Lysine and threonine

45

Coenzyme in transamination

Vit B6

46

Removal of excess N from peripheral tissues is via

glutamine, alanine, glutaminase

47

Also known as the Krebs Henseleit Cycle/ Ornithine cycle

Urea cycle