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Flashcards in General Sepsis Deck (17):
1

Define colonisation

Presence of a microbe in the human body without an inflammatory response

2

Define infection

Inflammation due to a microbe

3

Define bacteraemia

Presence of viable bacteria in the blood

4

Define sepsis

Life-threatening organ dysfunction caused by a dysregulated host response to infection

5

Define septic shock

Subset of sepsis
Circulatory and cellular/metabolic dysfunciton associated with a higher risk of mortality

Patient has sepsis + you have tried to resuscitate but afte adequate attempts they are still not responding to treatment

6

Will septicaemia ever be the answer to any question?

NO

7

Define virulence

Likelihood of causing disease

8

Define opportunistic pathogen

Infectious microorganism that is normally commensal/does not harm host but can cause disease when host's resistance is low e.g. immunosuppression

9

What is an accidental pathogen?

Pure random one
example - infection from a monkey

Like proper random

10

What are the local signs/symptoms of sepsis?

Pain
Tenderness
Guarding
Blood PR if appropriate

11

What are the systemic signs/symptoms of sepsis?

Fever
Chills/rigors
Nausea/vomiting
Constipation/diarrhoea
Malaise/anorexia

12

What causes peritonitis?

Leakage of bowel contents into sterile peritoneal cavity

13

Leaky blood vessels happen in sepsis. True or false?

True

14

What does a patient have to score on SIRS in order to be diagnosed with sepsis?

2 or more

15

How many points on qSOFA does a patient need for sepsis to be considered?

2 or more

16

What does a patient have to score on a NEWS chart for sepsis to be considered?

5 or more

17

What is sepsis 6?

Take 3
-Blood culture
-Lactate (FBC + biochemistry)
-Monitor urine output (catheterise)

Give 3
-High flow oxygen
-Fluids
-IV antibiotics