The antibiotic man

Question 1

What antibiotic can be used as an alternative to gentamicin?

Answer 1

Aztreonam

Question 2

What stain of bacteria is gentamicin active against

Answer 2

Gram negative

Question 3

What stain of bacteria is vancomycin active against?

Answer 3

Gram positive

Question 4

What antibiotic is very good for covering anaerobes?

Answer 4

Metronidazole

Question 5

If NEWS is > 5 what should you consider?

Answer 5

SEPSIS

Question 6

How long do you have to complete the sepsis 6 bundle?

Answer 6

1 HOUR

Question 7

What is the treatment for epiglottitis/supraglottitis?

Answer 7

Ceftriaxone

Question 8

What is the treatment for mild/mod community acquired pneumonia?

Answer 8

Amoxicillin (IV/PO) 5 days

If penicillin allergic:
Doxycycline

Question 9

What is the treatment for severe community acquired pneumonia?

Answer 9

Co-amoxiclav IV + Doxycycline PO

If penicillin allergic - Levofloxacin IV

Question 10

If a patient is in ICU or HDU with community acquired pneumonia, what antibiotics should they be given?

Answer 10

Co-amoxiclav IV
Clarithromycin IV

If penicillin allergic:
Levofloxacin IV

Question 11

What is the step down for severe community acquired pneumonia when the patient is transferred from IV treatment to oral treatment?

Answer 11

Doxycycline

Question 12

What is the treatment for a severe hospital acquired pneumonia?

Answer 12

IV amoxicillin and gentamicin

If penicillin allergic:
IV Co-trimoxazole + gentamicin

Question 13

What is the step down from IV to oral therapy for a patient who had severe hospital acquired pneumonia?

Answer 13

Co-trimoxazole

Question 14

What is the treatment for a non-severe hospital acquired pneumonia?

Answer 14

PO amoxicillin 5 days

If penicillin allergic: doxycycline

Question 15

When should antibiotics be given in an exacerbation of COPD?

Answer 15

If high sputum purulence or consolidation on CXR or signs of pneumonia

Question 16

What is the antibiotic treatment for an exacerbation of COPD?

Answer 16

Amoxicillin

If penicillin allergic: doxycycline

Question 17

What is the treatment for native valve indolent endocarditis?

Answer 17

Amoxicillin IV +

Gentamicin IV

Question 18

What is the treatment for native valve severe sepsis endocarditis?

Answer 18

Flucloxacillin IV

Question 19

What is the treatment for prosthetic valve endocarditis or suspected MRSA?

Answer 19

Vancomycin IV
Gentamicin IV

When therapeutic levels reached, add rifampicin PO

Question 20

What is the treatment for non severe C.diff?

Answer 20

Metronidazole PO

Question 21

What is the treatment for severe C.diff?

Answer 21

Vancomycin PO +/- IV metronidazole

Question 22

What is the treatment for peritonitis/biliary tract/Intra-abdominal infections?

Answer 22

IV amoxicillin + metronidazole + gentamicin

If penicillin allergic: IV Vancomycin + metronidazole + gentamicin

Step down to PO co-trimoxazole and metronidazole

Question 23

What is the treatment for proven spontaneous bacterial peritonitis (severe)?

Answer 23

Pip-taz IV

Step down to co-trimoxazole

Question 24

What is the treatment for proven spontaneous bacterial peritonitis (mild)?

Answer 24

Co-trimoxazole PO

Question 25

Should you treat a UTI in a patient with a catheter and no clinical signs/symptoms of infection?

Answer 25

No | If definite infection, treat as complicated UTI

Question 26

What is the treatment for an uncomplicated female lower UTI?

Answer 26

Nitrofurantoin or trimethoprim

Question 27

What is the treatment for an uncatheterised male UTI?

Answer 27

Nitrofurantoin or trimethoprim

Question 28

Should you treat a UTI in older adults if they are asymptomatic?

Answer 28

No

Question 29

What is the treatment for a complicated UTI/Pylonephritis/Urosepsis?

Answer 29

IV amoxicilliln and gentamicin If penicillin allergic: IV co-trimoxazole and gentamicin Step down to PO co-trimoxazole or as per sensitivities

Question 30

What is the treatment for cellulitis?

Answer 30

Flucloxacillin IV/PO If penicillin allergic: Doxycycline PO

Question 31

What is the treatment for a mild diabetic foot infection?

Answer 31

Fluclox or doxycycline

Question 32

What is the treatment for a moderate diabetic foot infection?

Answer 32

Fluclox + metronidazole Or doxycycline + metronidazole

Question 33

What is the treatment for open fracture prophylaxis?

Answer 33

IV Cefuroxime

Question 34

What is the treatment for meningitis?

Answer 34

Ceftriaxone and dexamethasone started for 4 days or with antibiotics.

Question 35

What should you add to meningitis treatment if you suspect encephalitis?

Answer 35

Aciclovir

Question 36

What should you add to meningitis treatment if the patient is immunocompromised or over 60?

Answer 36

Amoxicillin

Question 37

What is the treatment for oral thrush?

Answer 37

Miconazole gel

Question 38

What is the treatment for non-severe hospital acquired pneumonia?

Answer 38

Amoxicillin If penicillin allergic: doxycycline

Question 39

What is the treatment for non-severe aspiration pneumonia?

Answer 39

Amoxicillin and metronidazole If penicillin allergic: doxycycline and metronidazole

Question 40

What is the treatment for severe aspiration pneumonia

Answer 40

IV amoxicillin, gentamicin and metronidazole If penicillin allergic, replace amox with doxycycline or clarithromycin

Question 41

What is the step down to oral for severe aspiration pneumonia?

Answer 41

Amoxicillin and metronidazole If penicillin allergic: doxycycline and metronidazole

Question 42

What is the treatment for an acute cough/bronchitis?

Answer 42

Give no significant benefit. Only give in frail elderly. Amoxicillin or doxycycline if allergic

Question 43

What is the treatment for acute septic arthritis/osteomyelitis?

Answer 43

Flucloxacillin IV

Question 44

What is the treatment for a severe systemic infection of unknown source?

Answer 44

Amox, met and gent Vanc, met and gent