Genes, Transcription, Mitosis, Meiosis Flashcards

(95 cards)

1
Q

A chromosome contains ______ ___ _____ ______

A

Millions of base pairs

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2
Q

What is another word to describe a nucleotide polymer?

A

A polynucleotide

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3
Q

T/F: Nitrogenous bases are basic (pH wise)

A

True!

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4
Q

Nitrogenous bases can be divided into 2 group types; what do these 2 groups consist of?

A
  1. Thymine + Cytosine (single-ring structures)
  2. Adenine + Guanine (larger, double-ring structures)
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5
Q

RNA contains ________ sugars whereas DNA contains __________ sugars

A
  1. Ribose
  2. Deoxyribose
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6
Q

DNA is composed of a ______ ________ backbone

A

Sugar phosphate

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7
Q

What are the 2 main functions of DNA polymerase?

A
  1. DNA replication
  2. Repairing DNA that has been damaged (i.e. toxic chemicals or high energy radiation)
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8
Q

Which process happens first; transcription or translation?

A

Transcription

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9
Q

What are DNA polymerases?

A

Enzymes that synthesize DNA

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10
Q

What is a genotype?

A

An organisms’ genetic makeup

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11
Q

What is a phenotype?

A

An organisms’ physical individual traits

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12
Q

What is transcription?

A

The transfer of genetic information from DNA into an RNA molecule

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13
Q

What is translation?

A

The transfer of genetic information from mRNA into a polypeptide (protein strand)

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14
Q

What is the main function of a DNA gene?

A

To dictate the production of a polypeptide

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15
Q

What are codons?

A

A sequence of 3 nucleotides in DNA that encodes information for the production of a specific amino acid or serves as a stop signal to terminate protein synthesis

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16
Q

What are anticodons?

A

Anticodons are sequences of nucleotides that are complementary to codons, and are found in tRNAs

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17
Q

What are chromosomes?

A

A threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes

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18
Q

What is the function of a DNA helicase?

A

Unzips the double strand of DNA

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19
Q

What is the main function of a DNA polymerase?

Think of DNA replication

A

To synthesize DNA by adding nucleotides one by one to help form a DNA chain

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20
Q

T/F: DNA is fully conservative

A

False! DNA is semi-conservative when it comes to its replication process

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21
Q

T/F: DNA is directional

A

True, but DNA polymerase only runs 1 way

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22
Q

DNA is wrapped around _________ __________?

A

Histone proteins

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23
Q

What is the difference between sister chromatids and chromosomes?

A

Sister chromatids are duplicated DNA pairs that are connected at the centromere but separate DNA pairs are known as chromosomes

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24
Q

What is a diploid?

A

When you have 2 homologous chromosomes; contains two complete sets of chromosomes

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25
What is a haploid?
Cells that contains one complete set of chromosomes; one member of of each pair of homologous chromosomes
26
What is the point of meiosis?
To divide cells to go from diploid cells to haploid through 2 rounds of division through PMAT I & II (to get cells that look different from parental cells)
27
T/F: DNA is antiparallel (strands)
True! Remember 5' (prime) to 3' (prime) and 3' to 5'
28
What is the purpose of mitosis?
To replicate chromosomes which will eventually get separated into two separate nuclei
29
What are all 5 stages of mitosis? (Include the stage before prophase 0-5)
0. Interphase 1. Prophase 2. Metaphase 3. Anaphase 4. Telophase 5. Cytokinesis
30
The cell cycle consists of:
1. Interphase and M phase 2. Division
31
What is biotechnology?
The use of an organism or a component of an organism to make a product/process
32
How does genetic recombination occur naturally?
Through the process of Meiosis
33
What process occurs in cell division?
Reproduction
34
What is the name of the two cells that get created and are a result of cell division?
Daughter cells; they are genetically identical to each other and the original "parent" cell
35
Chromosomes contain most of the cell's _______?
DNA
36
What is asexual reproduction?
The creation of genetically identical offspring from a single parent without the presence of sperm or eggs
37
What type of cell division (process) is responsible for the growth, maintenance and asexual reproduction of multicellular organisms?
Mitosis
38
How does sexual reproduction differ from asexual reproduction?
Sexual reproduction requires fertilization of sperm to egg; asexual reproduction does not include sperm or eggs
39
What are gametes?
Egg and sperm cells
40
T/F: Meiosis only occurs in reproductive organs
True!
41
T/F: Gametes do not have half as many chromosomes as the parent cell that gave rise to it
False! Gametes DO have half as many chromosomes from the involved parent cell
42
What type of cell division (process) is responsible for the reproduction of cells?
Meiosis
43
Chromosomes are made up of a material called _______
Chromatin
44
What are histones?
Small proteins that are associated with DNA (all packed up)
45
What are nucleosomes?
Beads that attach to DNA that is wound around several histone molecules
46
Y/N: Before a cell divides, do chromosomes condense even further?
Yes! A cell must compact its DNA before it can divide or move to a new cell
47
What are sister chromatids?
Two identical copies of the same chromosome formed by DNA replication
48
What process MUST happen before cell division?
The duplication of all chromosomes
49
Chromosome duplication leads to _______ _________?
Sister chromatids
50
Once the cell divides, the sister chromatids ________ where they once again become a __________ where each _______ gets distributed to one individual ________ _____.
Separate; chromosome; chromosome; daughter cell
51
What are centromeres?
The linkage point between two sister chromatids
52
What is the cell cycle?
The "lifetime" of a cell; the process of birth to its own reproduction
53
T/F: Most of the cell cycle is not spent in interphase
False! Most of the time, cells are hanging out in interphase
54
What happens in the stage of Interphase in a cell cycle?
Cells perform their normal functions within an organism
55
What are the 3 sub-phases of Interphase?
1. G1 stage (first gap) *growth* 2. S phase (DNA synthesis & chromosome duplication) 3. G2 stage (second gap) *growth*
56
What part of the cell cycle deals with the division of cells?
Mitosis (mitotic phase)
57
What happens during cytokinesis?
The cytoplasm and all of the cell's organelles are divided into 2 cells
58
What are mitotic spindles?
Structures that are attached to centrosomes that form during cell division and separates duplicated chromosomes by latching on to the centromere
59
What are centrosomes?
Organelles that serve as a main microtubule organizing center of a eukaryotic cell
60
T/F: Asexual reproduction offspring are exact genetic replicas of that one parent and of each other
True!
61
T/F: Each offspring of sexual reproduction inherits a unique combination of genes from both parents
True!
62
Somatic cells can be more simply thought of as ____ _____
Body cells
63
A typical human body cell contains how many chromosomes?
46
64
What are homologous chromosomes?
Chromosomes that carry genes that are controlling the same inherited characteristics (i.e. freckles at the same location on the duplicated sister chromatids; same gene at same location for both)
65
T/F: 2 homologous chromosomes can have different versions of the same gene
True
66
What are sex chromosomes?
Chromosomes that determine a person's sex (male/female)
67
FITB: Males have one X chromosome and one ___ chromosome
Y
68
FITB: Females have 2 ___ chromosomes
X
69
What is the diploid number in human cells?
46 (2n)
70
What is the haploid number in human cells?
23 (n)
71
What process occurs when a haploid sperm fuses with a haploid egg? (It starts with an F and ends with an N)
Fertilization
72
What are zygotes?
Fertilized eggs
73
T/F: Zygotes are not diploid
False! They are diploid due to the fact that a sperm must fertilize an egg (two components to make 1 product; which is the zygote)
74
T/F: Producing haploid (NOT DIPLOID) gametes through the process of meiosis keeps the chromosome number from doubling in every generation
True!
75
What are non-sister chromatids?
Chromatids that consist of one maternal chromatid and one paternal chromatid of a homologous pair
76
What is the difference between gametes and zygotes?
Gametes are sperm and egg; zygotes are eukaryotic cells
77
What are the 6 components of Transcription?
1. Gene 2. Messenger RNA 3. RNA polymerase 4. Promoter 5. Template strand 6. Non-template strand
78
T/F: DNA and RNA are nucleic acids
True!
79
What is a frameshift mutation?
A mutation that involves removal or insertion of nucleotides (base pairs) and alters the original sequence of base pairs
80
What are the two steps in protein synthesis?
1. Transcription (DNA → mRNA) 2. Translation (mRNA → protein)
81
T/F: In transcription, RNA polymerase will add complementary bases to a DNA coding strand
True!
82
T/F: RNA polymerase adding complementary bases to a complete DNA coding strand (replication) is called mRNA
True!
83
Uncoiled stringy DNA is also known as ____________.
Chromatin
84
Before mitosis occurs, what action does DNA do?
Replication
85
Why is mitosis important?
To help with growth, development and healing processes
86
In mitosis, what happens during Prophase?
Chromosomes condense and are visible within the nucleus, chromosomes move to opposite ends of the cell, nucleus eventually disintegrates
87
Each half of a chromosome is known as a ________ __________.
Sister chromatid
88
T/F: Sister chromatids of a chromosome are not identical to one another
False; they are identical
89
What happens in Metaphase in Mitosis?
Chromosomes move single file to the center of the cell along the metaphase plate
90
What happens in Anaphase in Mitosis?
Sister chromatids are split apart
91
What happens in Telophase in Mitosis?
2 diploid daughter cells are being created and the nucleus gets reformed in both daughter cells. Then the chromosomes uncoil to make chromatin again.
92
In the cells of some organisms, mitosis occurs without cytokinesis. This will result in _________
Cells with more than 1 nucleus
93
Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely _______ cell in ________
A plant; Cytokinesis
94
Stages of Mitosis in order (5 steps)
1. Prophase 2. Metaphase 3. Anaphase 4. Telophase 5. Cytokinesis
95