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Flashcards in genital tract infections Deck (60)
1

Bv - lt - ph? what kind of cells? buzzwords? 2 types of bacteria? treatment?

over 4.5,CLUE CELLS, thin, watery, fishy smelling vaginal discharge, mobiluncus and gardenia vaginalis, oral metronidazole

2

risk factors for thrush?4

poorly controlled diabetes, recent antibiotic treatment, high oestrogen, immunocompromised

3

how does it present?

intensely itchy with white vaginal discharge

4

organism responsible for thrush?

candida albicans

5

treatment? ol cf

topical clotrimazole, oral fluconazole

6

on penis...can get typical spotty rash of candida____?

balanitis

7

what would prostate be like in prostatitis?

tender

8

for acute bacterial prostatitis (C), what are the three most likely organisms?

E Coli, Coliforms, enterocoCCus

9

IF THEY ARE UNDER 35, WHAT DO YOU NEED TO REMEMBER TO CHECK FOR?

chlamydia and gonorrhoea (first pass)

10

what sort of test would you do for culture and sensitivity of prostate?

mid stream

11

whats the treatment for AB prostatitis?

Ciprofloxacin 28 days

12

if high c diff risk...try?

trimethoprim

13

normal bacterial flora. lactobacteria produce what, which suppresses growth of other bacteria?

lactic acid +/- hydrogen peroxide

14

what other organisms found in vagina? (sparta)

strep viridians and group b haemolytic strep (Bee ins)

15

possibly small numbers of candida species. what would you find around group b h s?

zones of complete haemolysis

16

obligate intracellular bacteria, infects urethra, rectum, throat, eyes, endocervix?

chlamydia

17

why does it not stain with gram stain?

no peptidoglycan in cell wall (water)

18

what is more common, chlamydia or gon?

chlamydia is much more common

19

gonorrhoea. where does it affect? how would you describe the bacteria, does it survive outside body?

urethra, rectum, throat and eyes. gram -ve diplococci (2 kidney beans facing each other), no

20

most common presentation?

purulent discharge

21

diagnosis?

NAAT or PCR

22

NAAT can be performed on?

swab or urine, better swab.

23

what urine test would you do for males?

first pass

24

for females?

high vaginal or VVS

25

Gonorrhoea - you can do microscopy of urethral/EC swabs, and you can also culture in agar plates (endocervical, rectal and throat swabs)

y

26

syphilis. why is there a difficulty in diagnosing?

doesn't stain gram stain and also cannot be grown on culture. Diagnosis relies on PCR or blood testing

27

causative organism (nl)

treponema pallidum

28

how many stages in the ilness?

4

29

what is the first stage?

chancre lesion

30

is a chancre painful?

no

31

what is actually happening at this stage?

organism multiplies at inocculation site and gets in to blood stream

32

what happens at secondary stage?

large numbers of bacteria circulating in blood with multiple manifestations

33

latent stage? do you get symptoms?

no, low level multiplication of spirochaetes in the intimate of the small blood vessels.

34

Many years later, what do you get?

cardiovascular or neurovascular complications

35

microbiology of syphillis, what do you swab for PCR?

chancre

36

in terms of serology, what are you looking for?

specific and non specific antibodies to T Pallidum

37

What is the name of the non specific test that indicates tissue inflammation?

VDRL (non specific)

38

why is it useful?

in monitoring the response to therapy

39

2 specific serological test?

TPPA and TPHA

40

why are these not useful in monitoring response to therapy?

although they are specific for syphillis, they remain positive for life once you've had them

41

what are the two antibodies used as screening test for syphillis?

IgG and IgM ELISA

42

treatment is?

injectable long acting preparation of penicillin

43

which HPV causes genital warts?

6 and 11 (nyth)

44

describe the virus?

NON ENVELOPED icosohedral virus containing dsDNA

45

how are genital warts spread?

close genital skin contact

46

cryopodo, treatment for genital warts?

cryotherapy, podophylotoxin cream/ lotion

47

what vaccine is given to 11-13 year old girls and what does it immunise against?

quadrivalent vaccine, immunises against genital warts and cervical cancer

48

enveloped virus containing dsDNA?

genital herpes

49

which type of herpes simplex causes cold sores?

1

50

how is it spread?

genital/genital or genital/oral contact

51

in the primary infection, may be asymptomatic. where does virus replicate?

dermid and epidermis

52

where does it go from the skin?

gets into nerve endings of sensory autonomic nerves

53

what does it cause at the nerve endings?

inflammation, which causes pain. exquisitely painful multiple small vesicles

54

where does the virus migrate to, where it hides for life?

sacral root glanglion

55

how do you diagnose?

swab deroofed blister (PCR)

56

treatment?

aciclovir and pain relief

57

single celled protozoal parasite causing vaginal discharge and irritation in females?

trichomonas vaginalis

58

how does it divide?

binary fission

59

how do you test for it?

high vaginal swab for microscopy

60

treatment? (flush)

oral metronidazole