Genitourinary/Reproductive System (Exam One) Flashcards
(149 cards)
What is the last major organ system that is perfused from the abdominal aorta?
Renal system
How much blood should circulate to the kidneys every minute?
1200 mL per minute
What is the uretropelvic junction (UPJ)?
Narrow point where each ureter joins the kidney
What is the ureterovesical junction (UVJ)?
Point where each ureter inserts the side of the bladder
What does proper anatomy of the UVJ help prevent?
- Urine reflux
- Infection
What is the detrusor?
Bladder muscle responsible for filling and emptying the bladder
True or False: The pelvic cavity can hold a large amount of fluid or bleeding before signs and symptoms appear.
True
What is the length of the urethra for a male?
8 to 10 inches
What is the length of the urethra for a female?
1 to 2 inches
What is hypospadias and epispadias?
Congenital malformation of male urethra
Where is the urethral meatus positioned with hypospadias?
Urethral meatus is abnormally placed on ventral (underside) of penis
Where is the urethral meatus positioned with epispadias?
Urethral meatus is abnormally placed on dorsal (topside) of penis
Are babies born with hypospadias or epispadias circumcised at birth? Why or why not?
- No
- The foreskin is used during reconstruction surgery
What is the functional unit of the kidney?
Nephron
What are the functions of the kidneys? Which is the primary function?
- Filtration of blood (primary)
- Create urine
- Rid the body of waste in the form of urine: urea, bacterial toxins, water-soluble drugs, drug metabolites
- Excrete or conserve fluid
- Keep electrolytes balance
- Acid-base balance
- Activate vitamin D
- Produce erythropoietin
- Produce renin (for RAAS)
- Regulates blood pressure
What is the normal blood pH?
7.35 - 7.45
What organ regulates the Renin-Angiotensin-Aldosterone System?
- Kidneys
- The kidneys will release renin to activate RAAS
What conditions would cause the kidneys to activate the Renin-Angiotensin-Aldosterone System?
- Decreased blood flow to the kidneys (decreased renal perfusion/renal ischemia)
- Decreased arterial blood pressure (i.e. hypotension)
- Decreased blood volume
- Decreased serum sodium (hyponatremia)
- Increased urine sodium
What is the purpose of the Renin-Angiotensin-Aldosterone System?
- To retain sodium, thus retaining fluid
- Increasing blood volume & increasing blood pressure
- Increasing serum sodium levels
- Increase renal perfusion
What are the steps of the Renin-Angiotensin-Aldosterone System?
- Kidneys release Renin
- Renin meets up with Angiotensinogen (which comes from the liver)
- Chemical reaction occurs between Renin & Angiotensinogen –> Angiotensin I is created
- Angiotensin Converting Enzyme (which comes from the lungs) converts Angiotensin I to Angiotensin II
- Angiotensin II promotes vasoconstriction of the arteries/arterioles
- Angiotensin II acts on the adrenal cortex, releasing aldosterone
- Aldosterone acts on the kidneys to retain sodium
- Retention of sodium causes fluid to be retained & potassium to be excreted
- Blood volume increases, blood pressure increases, renal perfusion increases, serum sodium levels increases
- When blood pressure is an appropriate level, the kidneys will stop releasing Renin and will stop RAAS
What is a normal GFR?
120 mL/min
What is a normal eGFR?
> 60 mL/min
What substances can be reabsorbed into the blood after filtration?
- Water
- Sodium
- Chloride
- Calcium
- Bicarbonate
What substances filter out into the urine?
- Potassium
- Hydrogen ions
- Ammonia