GI 09 Flashcards

(39 cards)

1
Q

Constipation ki ?

A

Hard to empty their bowels, or have infrequent bowel movements.

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2
Q

Goal of Treatment of Constipation ?

A

3 goals

  1. Identify and treat secondary causes.
  2. Relieve symptoms
  3. Restore normal bowel function.
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3
Q

Non pharmacological Treatment of constipation

A
  • Increase dietary fiber
  • Drink at least 2 L of fluid.
  • Exercise 10-15 minuates each day.
  • Respond to urge of bowel movement.
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4
Q

Pharmacological treatment for constipation?

A

Laxatives

  1. Bulk-forming laxatives
  2. Stool softeners
  3. Stimulant laxatives
  4. Osmotic laxatives.
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5
Q

Constipation 1.Bulk forming laxatives

A

Ex: Metamucil

  • Create mass and then promotes stool by peristalsis/wave of the intestinal wall.
  • The effect can see 12-24 hours or 72 hours
  • Side effect: Flatulence, abdominal distension
  • Safe in pregnancy and good for them.
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6
Q

Poloxamer ki ?

A

Non-ionic surfactant with similar properties like docusate.

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7
Q

Pharmacological treatment of Constipation 2. Stool softener ?

A

Ex: Coloxyl oral drops
-Good for Mild constipation (similar like docusate) Specially prevention of haemorrhoids.

-Work as softener and stimulant.

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8
Q

Pharmacological treatment of Constipation 3. Stimulant laxative.

A

Ex:Coloxyl (Bisacodyl)

  • Increase Gut motility and irritate colon lining to create contraction.
  • Quick 6-12hurs
  • Abuse can lead to weight loss
  • So monitoring required
  • Identify and refuse to sell or recommended to go to dr.
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9
Q

Pharmacological treatment of Constipation 4.Osmotic laxative

A

Ex:Laevolac
Retaining fluid in the bowel
Side effects: Flatulence and abdominal pain
Can work quick for some ppl but not for all

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10
Q

Diarrhoea ?

A

Increase frequency of loosen stool with cramp and pain.

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11
Q

Common causes of diarrhoea ?

A
  • Viruses and bacteria (most common cause)
  • Medications
  • Irritable Bowel Syndrome (IBS)
  • Medical conditions (coeliac disease, inflammatory bowel disease)
  • Diet or food intolerances (e.g. lactose intolerance)
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12
Q

Red flags for Diarrhoea

A

Elderly, children and infents. as they can go to dehydration faster.

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13
Q

Treatment GOAL of Diarrhoe

A
  • Relieve symptoms.
  • Hydration and
  • Treat underlying cause. Cause some times it can be sudden (food poisoning) and sometime it can be from long time.
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14
Q

Treatment of Diarrhoea? Non pharamcological

A

Oral rehydration therapy (ORT)
Avoid food which irretate the GUT. i.e spicy
Increase bulk forming food like bran and bananas.

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15
Q

Treatment of Diarrhoea? Non pharamcological

A

Oral rehydration therapy (ORT).
Avoid food which irretate the GUT. i.e spicy
Increase bulk forming food like bran and bananas.

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16
Q

Treatment of Diarrhoea? Pharmacological

A

• Anti-motility agents e.g. Loperamide. ( Increasing
intestinal transit time and absorption of water and
electrolytes. Loperamide also reduces urgency by
increasing anal sphincter tone).
• Adsorbents and bulk-forming agents e.g. psyllium. (Reduce diarrhoea
by reducing the fluid in stool and make
stool more solid).

17
Q

Oral rehydration therapy (ORT) ?

A

-Highly effective NP treatment for diarrhoea.
Ex: Enerlyte, Pedialyte, Hydralyte
-(NB)Sports drinks or other soda water has no sodium but sugar.

18
Q

Hemorrhoids

A

Hemorrhoids are swollen veins in the lower rectum.

  • Hemorrhoids/“piles”.
  • 50% of adults suffer at some point.
  • Vascular-rich connective tissue cushions become engorged( swell with blood) and swollen.
  • Two types: Internal or External.
19
Q

Causes and symptoms of of Haemorrhoids?

A

-Degeneration of connective tissue because of aging.
-Anal canal pressure from heavy lifting,
-Obesity, chronic diarrhea, Childbirth, standing for long
time.
-From constipation

Symptoms are: bleeding from rectal area.specially after a bowel motion.
And Pain

20
Q

Red flags for Haemorrhoids

A
  • 3 weeks or longer.
  • Sharp or stabbing pain
  • Going large volume of blood
  • Nausea, vomiting, loss of appetite
  • Over 50 old and complaining of change in bowel habit.
21
Q

Pharmacological and non-pharmacological treatment options for Haemorrhoids

A

Non-Pharmacological

  • Increase fibre in diet
  • Avoid becoming constipated
  • Pharmacological
  • anaesthetics
  • astringents: Zink make a protective code on haemorrhoids.
  • anti-inflammatories
22
Q

IBS Irritable bowel syndrome?

A

Functional disorder. So our Intestine may not contrac on time and relax on time as a result may causing a collection of symptoms
cramping, bloating, diarrhoea and constipation. On the other hand IBD is chronic & lead to more severe complications like weight loss fetigue cancer etc.

23
Q

IBS Non pharmacological treatment

A
  • Diet and lifestyle changes.
  • Smaller and more frequent meal.
  • Avoid alcohol, Caffine & Preserved food.
  • Manage stress
  • Hydration and Excercise.
24
Q

Pharmacological treatment options for IBS

A

Hyoscine Gastrosoothe for bloating and cramping.
Laxatives if constipation
Antidiarrhoeal-Loperamide.for slow down bowel movement.

25
Red flags for IBS
Under 16 Over 45 Severity of pain Blood in stool
26
Threadworms
- Known as pinworm - Small, thin, white worms between 2mm and 13mm - Children 5 and 14 age.
27
Transmission of Threadworms
- Ingestion of eggs by mouth or nose through inhalation. | - Person to person via contaminated clothes and bed linen.
28
Life Cycle of Threadworms
After ingestion larva hatched in the small intestine then adults establish into the colon. After ingestion by 1 month, they become ready to give egg and the lifespan is 2 months. Folds of ANAS female lay eggs nocturnally and migrate back to RECTUM.
29
Symptoms/ Clinical manifestations of Threadworms
Itchy anas Teeth grinding Loss of apitite Abdominal pain
30
Red flag for Threadworms
Pregnent Under 1 year Recent travel
31
Hygiene measures for Threadworms
Frequently change bedding Practice good hygine Treat the whole family.
32
Pharmacological treatment of Threadworm
-Mebendazole (VERMOX) (antihelmintic -distroy worm) Bind to Beta tubulin of worm result immobilization and death. Over 2 years 100 mg and repeat after 14 days. SE: Abdominal pain and diarrhoea. -Pyrantel (Nuromuscular blocking agent). Dose determines by body weight 10mg/kg SE same like mebendazole..
33
Diagnosis of threadworm ?
Via symptoms or looking for it. Look for worms in the anal region when asleep. Can use transparence tape.
34
Treatment options for Thredworm is and dose ?
mebendazole | Over 2 years 100 mg and repeat after 14 to 28 days
35
Mechanism of mebendazole
selective binding to beta tubulin of parasitic worm as a result immobilization and death.
36
Side effect of Mebendazole
Generally well tolarated | side effect cramp, diarrhoea, abdominal pain etc.
37
Pyrantel also can be an option for treatment for?
Thredworm
38
Mechanism of Pyrantel
Causing sudden contraction as a result paralysis of the worm and looses grip on the intestinal wall and expelled by peristalsis.
39
Adverse effects of Pyrantel
Well tolarated but some times may cause Diarrhoea ,cramp, pain.