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Flashcards in GI 1 Deck (22):
1

#1 cause of esophagitis

GERD

2

Barretts esophagus

metaplasia of lower esophagus (strat squamous change to columnar w/goblet cells), typically adenocarcinoma from GERD

3

MC GI cancer

adenocarcinoma

4

Mallory-Weiss Syndrome

longitudinal tears at gastric junction, presents w/hematemesis

5

How are esophageal varices developed?

portal HTN, asymptomatic till rupture where 40% die, tx w/propranolol

6

benign tumor of esophagus

leiomyoma

7

esophageal squamous cell carcinoma

5 year survival rate, 70% within one year

8

parietal cells

secrete HCl and intrinsic factor (help absorb B12)

9

chief cells

secrete pepsin

10

G cells

secrete gastrin, which stimulates secretino of gastric acid by parietal cells

11

hematemesis vs
melena

vomiting of blood, commonly from PUD
dark, digested blood

12

MCC of upper esophageal disease

peptic ulcer disease

13

gastric ulcer vs
duodenal ulcer

pain with food
pain goes away after eating bc of bicarb

14

how can NSAIDS cause PUD

block prostaglandins

15

benign gastric tumors

polyps
leiomyomas

16

Hirschsprung disease

aka toxic megacolon

17

transmural ischemic bowel disease complaints

-sudden pain out of proportion to physical signs
-bloody diarrhea
-abdominal pain after eating

18

true vs false diverticula

true contain all 3 layers of bowel
false only contains serosa and mucosal layer

19

MCC of SBO
LBO

adhesions from prior sx
mass

20

Celiac disease

genetic susceptibility HLA-DQ2

21

MC inflammatory bowel disease

-ulcerative colitis
large intestine, continuous ulcers
blood mucoid diarrhea
primary sclerosing cholangitis

22

Chrohns disease

transmural, affects entire GI tract
can get granulomas
skip/cobblestone appearance
macrocytic anemia (B12)