GI

Question 1

Treatment of locally advanced esophageal cancer

Answer 1

Neoadjuvant chemoradiation with carbo and paclitaxel (no traztuzumab)

Question 2

Second line therapy for metastatic esophageal cancer

Answer 2

Ramucirumab

Question 3

First line therapy for metastatic esophageal cancer

Answer 3

FOLFOX+/- Traztuzumab

Question 4

Risk factors for adenocarcinoma of esophagus (3)

Answer 4

Obesity, Barret’s, GERD

Question 5

Risk factors for squamous cell carcinoma of esophagus

Answer 5

Smoking, alcohol, ionizing radiation

Question 6

Treatment of local esophageal cancer in poor surgical candidate

Answer 6

Endoscopic mucosal resection

Question 7

Gene for hereditary diffuse gastric cancer

Answer 7

CDH1

Question 8

Management of hereditary diffuse gastric cancer

Answer 8

prophylatic gastrectomy

Question 9

Management of resectable gastric cancer (2)

Answer 9

Neoadjuvant ECF

Adjuvant 5FU + radiation

Question 10

Treatment of HER2 mutated metastatic gastric cancer

Answer 10

trastuzumab + cisplatin/5FU

Question 11

Treatment of HER2- metastatic gastric cancer

Answer 11

ECF or FOLFOX

Question 12

Second line treatment of metastatic gastric cancer

Answer 12

ramcirumab+paclitaxel

Question 13

HNPCC genes (3)

Answer 13

MSH2
MSH6
PMS2

Question 14

FAP gene

Answer 14

APC

Question 15

Cowden syndrome gene

Answer 15

PTEN

Question 16

Gene with resistance to anti-EGFR therapy

Answer 16

NRAS or KRAS

Question 17

Surgical approach for rectal tumor in distal one third of recturm

Answer 17

Abdominoperineal resection (APR)

Question 18

Surgical approach for proximal two thirds of the rectum

Answer 18

Low anterior resection (LAR)

Question 19

Adjuvant CRC treatment

Answer 19

FOLFOX

Question 20

Treatment of resectable rectal cancer

Answer 20

chemoradiation -> surgery -> adjuvant chemo

Question 21

Treatment of metastatic RAS WT CRC left sided

Answer 21

FOLFOXIRI (or FOLFOX) + cetuximab/panitumumab

Question 22

Treatment of metastatic RAS mt CRC right sided

Answer 22

FOLFOXIRI (or FOLFOX) = bevacizumab

Question 23

Adjuvant pancreatic cancer Tx in fit patients

Answer 23

FOLFIRINOX

Question 24

Adjuvant pancreatic cancer in unfit patients

Answer 24

Gem/Cis

Question 25

EpCAM mutation disorder

Answer 25

Indirectly causes Lynch

Question 26

Mutation associated with 5FU toxicity

Answer 26

DPYD

Question 27

Other tumors associated with FAP (2)

Answer 27

Desmoid tumors | Duodenal adenoma

Question 28

TACE vs RFA for HCC

Answer 28

TACE for larger tumors (>4cm), RFA for smaller

Question 29

Initial treatment for SCC anal cancer

Answer 29

CRT with 5-FU and mitomycin c

Question 30

When to assess response after first line CRT in anal cancer

Answer 30

26 weeks

Question 31

Treatment locoregional failure in rectal cancer

Answer 31

Surgery (APR)

Question 32

First line treatment for metastatic rectal cancer

Answer 32

Cisplastin + 5FU

Question 33

Adjuvant therapy for pancreatic cancer

Answer 33

Gem+capcitabine or FOLFIRINOX

Question 34

Neoadjuvant therapy for pancreatic cancer

Answer 34

FOLFIRINOX

Question 35

Chemotherapy for metastatic biliary cancer

Answer 35

Gem+cis

Question 36

Imaging findings for HCC (arterial, venous, and delayed phase findings)

Answer 36

Arterial: increased Venous: decreased Delayed: persistent washout