GI cancers Flashcards
1
Q
Risk factors for development of colorectal cancer?
A
Family history IBD Polyposis syndrome Nulliparity Early menopause Red-meat diet Low fibre diet Sedentary lifestyle Smoking Diabetes mellitus
2
Q
Types of colorectal cancer?
A
Adenocarcinoma
Carcinoid tumours
Stromal cell tumours
Lymphomas
3
Q
Left colon cancer presenting symptoms?
A
Colicky pain Rectal bleeding Bowel obstruction Tenesmus Mass LIF Early bowel habit change Less advanced disease
4
Q
Right colon cancer presenting symptoms?
A
Weight loss Anaemia Occult bleeding Mass in right iliac fossa Advanced disease
5
Q
Dukes A?
A
Confined to mucosa
6
Q
Dukes B?
A
Infiltration through muscle
7
Q
Dukes C?
A
Lymph node involvement?
8
Q
Dukes D?
A
Distant metastases
9
Q
FAP?
A
Familial adenomatous polyposis
APC gene mutation
10
Q
HNPCC?
A
DNA repair gene mutation
Also endometrial cancer
11
Q
Most common site of mets for colon cancer?
A
Liver
12
Q
Tumour marker for colorectal?
A
CEA
13
Q
Symptoms of oesophageal cancer?
A
Progressive dysphagia Weight loss Anorexia Vomiting Hoarseness Melaena Retrosternal pain Intractable hiccups
14
Q
Risk factors for oesophageal cancer?
A
Cigarette smoking
Alcohol consumption
Barrett’s oesophagus
Chronic inflammation
15
Q
Types of oesophageal cancer?
A
Squamous cell
Adenocarcinoma
