GI cancers Flashcards
(16 cards)
Risk factors for development of colorectal cancer?
Family history IBD Polyposis syndrome Nulliparity Early menopause Red-meat diet Low fibre diet Sedentary lifestyle Smoking Diabetes mellitus
Types of colorectal cancer?
Adenocarcinoma
Carcinoid tumours
Stromal cell tumours
Lymphomas
Left colon cancer presenting symptoms?
Colicky pain Rectal bleeding Bowel obstruction Tenesmus Mass LIF Early bowel habit change Less advanced disease
Right colon cancer presenting symptoms?
Weight loss Anaemia Occult bleeding Mass in right iliac fossa Advanced disease
Dukes A?
Confined to mucosa
Dukes B?
Infiltration through muscle
Dukes C?
Lymph node involvement?
Dukes D?
Distant metastases
FAP?
Familial adenomatous polyposis
APC gene mutation
HNPCC?
DNA repair gene mutation
Also endometrial cancer
Most common site of mets for colon cancer?
Liver
Tumour marker for colorectal?
CEA
Symptoms of oesophageal cancer?
Progressive dysphagia Weight loss Anorexia Vomiting Hoarseness Melaena Retrosternal pain Intractable hiccups
Risk factors for oesophageal cancer?
Cigarette smoking
Alcohol consumption
Barrett’s oesophagus
Chronic inflammation
Types of oesophageal cancer?
Squamous cell
Adenocarcinoma
Sister Mary Joseph nodule?
In umbilicus Gastric cancer Colonic cancer Pancreatic cancer Endometriosis Infection