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CLINICAL MICROSCOPY > Glomerular Filtration Tests > Flashcards

Glomerular Filtration Tests Flashcards

1
Q

TRUE OR FALSE
Glomerular filtration test is NOT a valuable detector for early renal disease.

A

TRUE

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2
Q

Generally considered the best overall indicator of the level of kidney function

A

Glomerular filtration rate (GFR)

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3
Q

Clearance test is the _____________ test used to measure the _____________ of the _____________.

A

Clearance test is the STANDARD test used to measure the FILTERING CAPACITY of the GLOMERULI.

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4
Q

Greatest source of error in any clearance procedure using urine is

A

Improperly timed specimen

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5
Q

Inulin test is the

A

Gold standard for exogenous clearance test

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6
Q

Inulin is

A

not reabsorbed nor secreted by the tubules

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7
Q

This exogenous clearance test is valuable to measure the viability of a transplanted kidney

A

Radionucleotides

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8
Q

Solution or reagent used in Radionucleotides

A

Iothalamate/ 125 Iodine

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9
Q

Does Radionucleotide requires to collect urine for the test?

A

No.

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10
Q

Cons of Radionucleotide

A

Exogenous procedure
labor intensive
Costly

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11
Q

Earliest glomerular filtration test

A

UREA

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12
Q

They are for clearance test and for tubular integrity

A

Cystatin C and Beta 2 microglobulin

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13
Q

Cystatin C is a Small protein produced by all _____________ cells , filtered then reabsorbed and _____________ by
RTE.

A

Cystatin C is a Small protein produced by all NUCLEATED cells , filtered then reabsorbed and BROKEN DOWN by
RTE.

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14
Q

This reduces production of Cystatin C

A

Glucocorticoids (steroids)

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15
Q

Beta 2 Microglobulin is high in

A

LYMPHOCYTES

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16
Q

Beta 2 Microglobulin is not reliable for patient who has

A

Immune disorders

17
Q

Drugs that interferes and inhibit creatinine secretion

A

Gentamicin, cephalosporins and cimetidine

18
Q

True or False
Creatinine test has DIETARY restrictions

A

False

19
Q

Normal value of creatinine in MALE and FEMALE

A

Male: 107-139 mL/min
Female: 87-107 mL/min

20
Q

low molecular weight glycoprotein that functions as prostaglandin D synthase

A

Beta trace protein

21
Q

What does the MDRD (Modification of Diet in Renal Disease) require?

A

Age
Sex
Ethnicity

CLINICAL MICROSCOPY (4 decks)

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