Glucagon

Question 1

Class

Answer 1

Antihypoglycemic.
Pancreatic hormone.
Insulin antagonist.

Question 2

Actions

Answer 2

Converts liver glycogen to glucose to raise the blood sugar level, and inhibits glycogen synthesis.
Stimulates glucagon receptors in cardiac cells (in larger doses) and may be of benefit in beta blocker overdoses by increasing the force of contraction (+inotropic) and rate of contraction (+chronotropic), via cAMP, which also is positive inotropic, elevates plasma glucose, and causes smooth muscle relaxation.

Question 3

Indications

Answer 3

Hypoglycemia if no IV route available.
Beta blocker overdoses.
May be effective in some calcium channel blocker overdoses.

Question 4

Contraindications

Answer 4

Hypersensativity

Question 5

Side effects

Answer 5

N/V

Question 6

Precautions

Answer 6

Should not be used as a first line drug for hypoglycemia.

Will be ineffective in conditions where glycogen stores are depleted, i.e. chronic hypoglycemia, starvation.