GP - pharmacology Flashcards

(35 cards)

1
Q

What is the antibiotic treatment of tonsilitis?

A

penicillin
500 mg
qds
for 10 days

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2
Q

What is the antibiotic treatment for UTIs?

A

trimethoprim
200mg
bd
for 3 days

nitrofurantoin
500mg
qds
for 3 days

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3
Q

What is the antibiotic treatment for a LRTI, otitis media or sinusitis?

A

amoxicillin
500mg
tds
for 5 days

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4
Q

What things need to be on a controlled drug prescription?

A

dose, form of drug, strength, total quantity in words and figures, name and address of patient

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5
Q

How big are PRN doses compared to the 24 hour dose?

A

1/6

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6
Q

What are the 5 strong opioids?

A

morphine, bupenorphine, fentanyl, oxycodone, diamorphine

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7
Q

What are the weak opioids?

A

codeine, tramadol, dihydrocodiene

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8
Q

What are some simple analgesia?

A

paracetamol, ibuprofen

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9
Q

What are common SE of opioids?

A

constipation, nausea, sedation, dry mouth

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10
Q

What are some adjuvant pain killers?

A

antidepressants, antiepileptics, antispasmodics, benzos

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11
Q

What are the most common enzyme inducers?

A
PC BRAS (induce arrest)
phenytoin, carbamazepine, barbiturates, rifampicin, alcohol (chronic), sulphonylureas
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12
Q

What are the most common enzyme inhibitors?

A

AODEVICES (device inhibits)

allopurinol, omeprazole, disulfiram, erythromycin, valporate, isoniazid, ciprofloxacin, ethanol (acute), sulphonamide

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13
Q

What drugs should you stop before surgery?

A

I LACK OP
insulin, lithium, anticoagulants/antiplatelets, COCP/HRT, K-sparing diuretics, oral hypoglycaemics, perindopril and ACE-i

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14
Q

What should you stop with high K?

A

ACE-i
potassium addition to fluids
potassium sparing diuretics (e.g. amilodrine)

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15
Q

What is the pneumonic to remember basics of prescribing?

A
PReSCRIBER
Patient details
Reactions
Sign front of chart 
Contraindications 
Route 
IV fluids?
Blood clot prophylaxis?
anti-Emetics?
pain Relief?
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16
Q

What are SE/contraindications for steroids?

A
STEROIDS 
Stomach ulcers 
Thin skin 
oEdema 
Right and left heart failure
Osteoporosis 
Infection 
DM 
cushing's Syndrome
17
Q

What are SE/contraindications for NSAIDs?

A
NSAID 
No urine - renal failure 
Systolic dysfunction - heart failure 
Asthma 
Indigestion 
Dyscrasia - clotting abnormality
18
Q

What is the maximum dose of IV potassium?

19
Q

What is an example prescription for anti-emetic?

A

cyclizine 50mg 8-hrly

metoclopramide 10mg 8-hrly

20
Q

When should you avoid metoclopramide as anti-emetic?

A

PD - can exacerbate symptoms

young women - increased risk of dyskinesia

21
Q

What is first line for neuropathic pain?

A

amitriptyline or pregabalin

22
Q

What is the maximum dosage of paracetamol per day?

23
Q

What are 5 routes for medicines?

A
oral 
injection 
IV
rectal
topical 
vaginal 
inhaled
intrathecal
24
Q

How does naproxen work and what are some contraindications and cautions?

A

it inhibits COX 1 and 2, so reduces prostaglandins and inflammation and therefore pain (NSAID)
- caution with GI bleeds and ulcers, and asthma

25
What is the caution with metformin and radiology contrast?
contrast can cause kidney damage which would reduce the clearance of metformin so increase risk of lactic acidosis
26
How do ACE-i work? Why do they work less well in Afro-Caribean patients?
it stops angiotensin converting enzyme changing angiotensin I to II Afro-Caribbean people have more commonly repressed RAAS system
27
What are 3 medications that St. John's wort can interact with?
meds broken down by liver, depression meds, HIV/AIDS, pain, photosensitive drugs, warfarin, contraception
28
How do you treat acute hypoglycaemia?
10-20mg oral glucose follow 15-20 minutes later if needed Follow with starchy meal
29
What are some drugs with narrow therapeutic index?
warfarin, digoxin, phenytoin, theophylline
30
What are some types of drugs that require careful dosage control?
antihypertensive, antidiabetic drugs
31
What are some drugs with potent interactions with alcohol?
NSAIDs - GI bleeds metformin - lactic acidosis warfarin - increased anticoagulation monoamine oxidase inhibitors - hypertensive crisis metronidazole & disulfiram - sweating, flushing, nause and vomiting barbiturates, opioids and benzodiazepines - sedation
32
What are some causes of high neutrophils?
bacterial infection tissue damage - inflammation, infarct, malignancy steroids
33
What are some causes of low neutrophils?
viral infection chemo/radio clozapine carbimazole
34
What are some causes of high lymphocytes?
Viral infection lymphoma chronic lymphocytic leukemia
35
What can cause raised urea?
renal failure | upper GI bleed (Hb broken down by gastric acid into urea)